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Table 2 Multivariable predictors of treatment target achievement at 12 months

From: Individualised treatment targets in patients with type-2 diabetes and hypertension

 

Multivariable

OR (95% CI)

Age > median

 Yes vs. no

1.25 (1.071.45)

Female gender

 Yes vs. no

1.03 (0.91–1.17)

Diabetes duration > median

 Yes vs. no

0.65 (0.58–0.73)

Bodyweight > median

 Yes vs. no

0.91 (0.80–1.02)

HbA1c treatment target

 > 7.0% vs. ≤ 6.5%

3.02 (2.61–3.49)

 > 6.5 to ≤ 7.0% vs. ≤ 6.5%

5.31 (4.38–6.44)

HbA1c baseline tertile

 3rd tertile vs. 1st tertile

0.25 (0.22–0.30)

 2nd tertile vs. 1st tertile

0.15 (0.13–0.18)

Care-dependent

 Yes vs. no

0.84 (0.57–1.24)

Not working

 Yes vs. no

0.97 (0.83–1.14)

< 9 years of school education

 Yes vs. no

0.86 (0.76–0.98)

Patient lives alone

 Yes vs. no

0.88 (0.77–1.02)

< 1 h per week of physical activity

 Yes vs. no

0.93 (0.82–1.06)

Any vascular diseasea

 Yes vs. no

0.96 (0.84–1.09)

Any diabetes related diseaseb

 Yes vs. no

1.04 (0.90–1.20)

Other concomitant disease

 Yes vs. no

0.94 (0.84–1.06)

All lipid values available (< 6 weeks)c

 Yes vs. no

1.03 (0.90–1.18)

All BG values available (< 6 weeks)d

 Yes vs. no

1.29 (1.14–1.45)

All renal lab values availablee

 Yes vs. no

1.24 (1.09–1.41)

≥ 3 oral antidiabetic drugs at BL

 Yes vs. no

0.59 (0.49–0.72)

People receiving any insulin

 Yes vs. no

0.82 (0.70–0.97)

≥3 antihypertensive drugs at BL

 Yes vs. no

1.07 (0.95–1.21)

Any non-severe hypoglycaemiaf

 Yes vs. no

0.95 (0.74–1.23)

Any severe hypoglycaemiag

 Yes vs. no

0.53 (0.25–1.13)

  1. HbA1c glycated haemoglobin, BG blood glucose
  2. aAny of CAD, prior MI, prior PCI, prior CABG, prior stroke, prior diagnosis of HF
  3. bAny of neuropathy, retinopathy, laser coagulation, macular oedema, eye doctor visit, blindness, dialysis, or amputation
  4. cTotal cholesterol, HDL-C, LDL-C, and TG available
  5. dFasting blood glucose, postprandial blood glucose, and HbA1c available
  6. eSerum creatinine and information on macroalbuminuria available
  7. fWithout symptoms, symptoms but without help, with help—but not medical help or hospitalisation
  8. gSymptoms with need for medical help or hospital admission. Patient numbers and univariate odds ratios are available in Additional file 2