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Table 5 Change rate of adipose-associated markers after treatment

From: The effect of dapagliflozin treatment on epicardial adipose tissue volume

 

Dapagliflozin (n = 20)

Conventional therapy (n = 20)

p value, dapagliflozin vs. conventional

ΔEAT volume (cm3)

− 16.4 ± 8.3**

4.7 ± 8.8

0.01

ΔTNF-α (pg/ml)

− 0.5 ± 0.7**

0.03 ± 0.3

0.03

ΔPAI-1 (ng/ml)

− 10.1 ± 18.8*

− 2.0 ± 9.7

0.18

  1. EAT epicardial adipose tissue, TNF-α tumor necrosis factor-α, PAI-1 plasminogen activator inhibitor-1
  2. Data are expressed as mean ± SD. ** p < 0.05 compared with baseline of each group, * p < 0.1 compared with baseline of each group
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Cardiovascular Diabetology

ISSN: 1475-2840