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Table 5 Peak of developed tension (DT, g/mm2) of left ventricular papillary muscle following positive inotropic stimulation

From: Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus

 

CTL

(n = 13)

CTL + APO

(n = 13)

DM

(n = 12)

DM + APO

(n = 13)

PP30

9.47 ± 2.36

9.44 ± 1.97

6.73 ± 3.23*

8.27 ± 2.29

[Ca2+]o 2.5 mM

8.61 ± 2.14

8.95 ± 1.87

6.28 ± 2.94*

7.60 ± 2.11

Iso 10−6 M

7.79 ± 2.32

7.86 ± 1.63

5.62 ± 2.61*

6.54 ± 2.06

  1. Data are expressed as mean ± standard deviation
  2. CTL control, CTL + APO control treated with apocynin, DM diabetes mellitus, DM + APO diabetes mellitus treated with apocynin, PP30 30-s post-rest contraction, [Ca2+] o 2.5 mM extracellular calcium concentration, Iso 10−6 M β-adrenergic agonist isoproterenol addition to the nutrient solution
  3. * p < 0.05 vs CTL
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Cardiovascular Diabetology

ISSN: 1475-2840