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Table 3 Echocardiographic left ventricular functional data

From: Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus

 

CTL

(n = 13)

CTL + APO

(n = 19)

DM

(n = 17)

DM + APO

(n = 16)

EFS (%)

53.3 ± 4.90

53.3 ± 5.45

49.0 ± 5.19*

46.9 ± 5.59#

EF

0.90 ± 0.03

0.89 ± 0.03

0.86 ± 0.04*

0.85 ± 0.05#

PWSV (mm/s)

38.1 ± 3.84

37.2 ± 3.51

27.9 ± 2.21*

30.2 ± 5.35#

S′ (cm/s)

3.50 (3.25–3.56)

3.50 (3.50–3.75)

3.00 (3.94–3.00)*

3.00 (2.50–3.00)#

Mitral E/A

1.46 ± 0.16

1.55 ± 0.28

1.29 ± 0.20

1.47 ± 0.30§

IVRT (ms)

28.9 ± 2.63

30.1 ± 3.12

38.6 ± 6.05*

38.6 ± 4.56#

E/E′

18.3 ± 3.51

18.8 ± 3.40

18.4 ± 3.01

19.7 ± 3.86

  1. Data are expressed as mean ± standard deviation or median and 25th and 75th percentiles
  2. CTL control, CTL + APO control treated with apocynin, DM diabetes mellitus, DM + APO diabetes mellitus treated with apocynin, EFS endocardial fractional shortening, EF ejection fraction, PWSV posterior wall shortening velocity, S′ tissue Doppler imaging of systolic velocity of the mitral annulus (average of septal and lateral wall), E/A ratio between early (E)-to-late (A) diastolic mitral inflow, IVRT isovolumic relaxation time, E′ tissue Doppler imaging of early diastolic velocity of mitral annulus (average of septal and lateral wall)
  3. * p < 0.05 vs CTL; # p < 0.05 vs CTL + APO; § p < 0.05 vs DM