| Normal (n = 6578) | Pre-diabetes (n = 4146) | Diabetes (n = 1717) | p |
---|---|---|---|---|
Age, years | 50 ± 8 | 53 ± 8* | 55 ± 9*†| < 0.001 |
Male, n (%) | 5423 (82.4) | 3523 (85.0) | 1526 (88.9) | <Â 0.001 |
Body mass index, kg/m2 | 24.1 ± 2.6 | 25.0 ± 2.8* | 25.2 ± 2.9*†| < 0.001 |
Waist circumference, cm | 85 ± 8 | 88 ± 8* | 89 ± 8*†| < 0.001 |
Systolic blood pressure, mmHg | 118 ± 15 | 122 ± 15* | 122 ± 16* | < 0.001 |
Diastolic blood pressure, mmHg | 74 ± 11 | 77 ± 10* | 76 ± 10* | < 0.001 |
Hypertension, n (%) | 1568 (24.4) | 1544 (39.1) | 924 (55.1) | <Â 0.001 |
Antihypertensive drugs, n (%) | 984 (17.0) | 1077 (30.2) | 675 (43.2) | <Â 0.001 |
Dyslipidemia, n (%) | 1481 (22.6) | 1286 (31.0) | 701 (40.8) | <Â 0.001 |
Lipid lowering drugs, n (%) | 89 (4.2) | 143 (10.8) | 76 (18.8) | <Â 0.001 |
Smoking, n (%) | 3919 (64.4) | 2552 (68.8) | 1166 (74.0) | <Â 0.001 |
Total cholesterol, mg/dL | 196 ± 33 | 203 ± 34* | 190 ± 36*†| < 0.001 |
Triglyceride, mg/dL | 130 ± 79 | 153 ± 96* | 156 ± 102* | < 0.001 |
HDL cholesterol, mg/dL | 54 ± 16 | 53 ± 16* | 51 ± 16*†| < 0.001 |
LDL cholesterol, mg/dL | 122 ± 31 | 125 ± 33* | 115 ± 33*†| < 0.001 |
Creatinine, mg/dL | 0.9 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.096 |
hs-CRP, mg/dL | 0.3 ± 1.5 | 0.4 ± 2.1 | 0.3 ± 1.7 | 0.086 |
Fasting glucose, mg/dL | 88 ± 7 | 100 ± 10* | 129 ± 35*†| < 0.001 |
HbA1C, % | 5.3 ± 0.3 | 5.7 ± 0.3* | 6.8 ± 1.1*†| < 0.001 |