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Table 4 Univariate and multivariable association of PWV, GLS and FMD % post treatment with parameters of the study population

From: Effects of 6-month treatment with the glucagon like peptide-1 analogue liraglutide on arterial stiffness, left ventricular myocardial deformation and oxidative stress in subjects with newly diagnosed type 2 diabetes

 

PWV > 10 m/s

GLS < -15%

FMD > 11%

Univariate

Multivariable

Univariate

Multivariable

Univariate

Multivariable

Odds ratio

p

Odds ratio

p

Odds ratio

p

Odds ratio

p

Odds ratio

p

Odds ratio

p

HbA1c

1.499 (1.1–1.7)

0.035

1.709 (1.1–1.9)

0.047

1.104 (0.9–2)

0.085

1.668 (1–2.1)

0.033

1.456 (1.2–1.5)

0.030

1.422 (1.1–1.4)

0.048

Weight

1.037 (1–1.1)

0.096

1.200 (0.9–1.3)

0.059

1.099 (1–1.1)

0.067

1.172 (0.9–1)

0.029

1.225 (1–1.3)

0.039

1.054 (0.9–1.3)

0.057

BMI

1.142 (0.9–1.4)

0.071

1.241 (1.1–2)

0.092

1.325 (1–1.5)

0.065

1.490 (0.9–1.6)

0.014

1.198 (0.9–1.3)

0.042

1.304 (0.9–1.5)

0.072

Waist

1.252 (1–1.3)

0.045

1.077 (0.9–1.4)

0.062

1.132 (1–1.5)

0.037

1.516 (1–2)

0.043

1.427 (0.9–1.6)

0.033

1.873 (1–1.9)

0.011

HR

1.100 (1–1.2)

0.010

1.210 (1–1.4)

0.022

1.070 (1–1.3)

0.053

1.094 (1–1.3)

0.205

1.505 (1.1–1.6)

0.069

1.783 (1.2–1.9)

0.061

Liraglutide

0.333 (0.2–1.3)

0.018

0.367 (0.2–1.7)

0.046

0.815 (0.3–1.5)

0.043

0.920 (0.4–1.4)

0.046

0.650 (0.4–1.5)

0.035

0.790 (0.6–1.7)

0.049

  1. The median values PWV, GLS and FMD of the makers were used in logistic regression analysis. PWV pulse wave velocity, GLS global longitudinal strain, FMD% percentage difference of flow mediated dilatation of brachial artery. Values are odd ratios (95% confidence intervals)