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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

Fig. 4

Diabetes associated impairment of systolic and diastolic function in diabetes. a Diabetes associated impairment of the following contractile parameters in type-1 and type-2 diabetes mellitus (T1DM, T2DM): end-systolic pressure–volume relationship (ESPVR), preload recruitable stroke work (PRSW), global circumferential strain (GCS) and the peak strain rate values in systole (SrS). b Diabetes associated alteration of diastolic parameters TauG, maximal slope of diastolic decrement (dP/dtmin) and strain rate at isovolumic relaxation (SrIVR) are shown. c Diabetes associated alteration of the slope of end-diastolic pressure–volume relationship (EDPVR), left ventricular end-diastolic pressure (LVEDP) and strain rate in early diastole (SrE) are shown. d Correlation analyses of GCS and SrS to ESPVR and PRSW are shown. e Correlation analyses of active relaxation parameter SrIVR to TauG and dP/dtmin are shown. f Correlation analyses of SrE to EDPVR and LVEDP are shown. Groups: animals with T1DM, their non-diabetic controls (T1DM Co); animals with T2DM and their non-diabetic controls (T2DM Co). *p < 0.05 T1DM vs. T2DM

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Cardiovascular Diabetology

ISSN: 1475-2840