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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking

Fig. 1

Sitagliptin reduced hyperglycemia and glucose intolerance in GK rats. a Body weight and plasma parameters were evaluated in the experimental model. TG, triglycerides; Ch, cholesterol, LDL and HDL, low- and high-density lipoproteins, respectively, and FFA, free FA. N = 10, each group. b Plasma glucose, insulin and GLP-1 were measured in fasting rats before (0 min) and after (15–60 min) an oral glucose loading (G). *p < 0.05 and **p < 0.01 vs. wistar. p < 0.05 and ††p < 0.01 vs. GK rats. §p < 0.05 vs. 15 min glucose-overload or fasting state. N = 7, each group

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