Patient characteristics | Risk category | LDL-C goal |
---|---|---|
CVD diagnosed by invasive or non-invasive testing, peripheral artery disease, any arterial revascularization, ischemic stroke; type 1 or type 2 diabetes mellitus with ≥ 1 CV risk factor and/or target organ damage; GFR < 30 ml/min/1.73 m2; and/or calculated SCORE ≥ 10% | Very high | < 1.8 mmol/l (~ 70 mg/dl) or a ≥ 50% LDL-C reduction when the target cannot be reached |
Markedly elevated single risk factors such as familial dyslipidemia and severe hypertension; type 1 or type 2 diabetes mellitus without CV risk factors or target organ damage; GFR 30–59 ml/min/1.73 m2; and/or calculated SCORE ≥ 5% and < 10% | High | < 2.5 mmol/l (~ 100 mg/dl) |
Calculated SCORE ≥ 1% and < 5% | Moderate | < 3.0 mmol/l (~ 115 mg/dl) |
Calculated SCOREÂ <Â 1% | Low | <Â 3.0Â mmol/l (~Â 115Â mg/dl) |