Fig. 2
From: DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho−/− mice
Effects of linagliptin treatment on body weight (a), survival rate (b), and alopecia (c) of klotho−/− mice. C, control group; L, linagliptin-treated group. Upper panels in c indicate the appearance of both groups of mice. Values are mean ± SEM. In a, b n = 15 in each group at day 0. In c n = 13 in control group, n = 15 in linagliptin-treated group. In b statistical significance was analyzed by a standard Kaplan–Meier analysis with a log rank test and χ2 analysis. In c statistical analysis was performed by Mann–Whitney U test