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Table 1 Population analysis

From: Type 2 diabetes mellitus is associated with a lower fibrous cap thickness but has no impact on calcification morphology: an intracoronary optical coherence tomography study

 

Non DM (35)

DM (56)

p value

Sex (male, %)

28 (80.0)

36 (64.3)

NS

Age (years)

70.7 ± 9.4

70.4 ± 5.9

NS

MAP (mmHg)

97 ± 12

96 ± 12

NS

BMI (kg/m2)

27.7 ± 4.2

30.9 ± 4.6

< 0.001

Positive family history (n, %)

17 (48.6)

25 (44.6)

NS

History of hypertension (n, %)

30 (85.7)

49 (87.5)

NS

Hyperlipidaemia (n, %)

16 (45.7)

39 (69.6)

0.04

Current smoking (n, %)

9 (25.7)

9 (16.1)

NS

Total pack years

32.7 ± 34.4

17.1 ± 22.2

< 0.001

COPD (n, %)

3 (8.6)

6 (10.7)

NS

Known CAD (n, %)

12 (34.3)

20 (35.7)

NS

Previous PCI (n, %)

11 (31.4)

14 (25.0)

NS

Previous CABG (n, %)

1 (2.9)

2 (3.6)

NS

Angina (CCS class)

1.9 ± 1.1

2.3 ± 0.7

NS

Dyspnoe (NYHA class)

1.6 ± 1.1

2.1 ± 0.8

NS

Duration of diabetes (years)

NA

11.9 ± 9.4

NA

Diabetic retinopathy (n, %)

NA

10 (17.9)

NA

Diabetic polyneuropathy (n, %)

NA

20 (35.7)

NA

Total cholesterol (mg/dl)

195.3 ± 43.8

191.2 ± 45.1

NS

LDL-cholesterol (mg/dl)

128.9 ± 39.6

117.8 ± 36.4

NS

HDL-cholesterol (mg/dl)

48 ± 13.2

44.2 ± 10.3

NS

HbA1c (%)

5.7 ± 0.4

7.2 ± 1.6

< 0.001

Medication prior to coronary angiography

 ASA (n, %)

31 (88.6)

52 (92.9)

NS

 ACEi/ARB (n, %)

24 (65.7)

40 (71.4)

NS

 β-Blocker (n, %)

24 (65.7)

46 (82.1)

NS

 Statine (n, %)

21 (60.0)

35 (62.5)

NS

  1. The data are presented as mean ± SD or n (%) and displayed with p values
  2. DM, diabetes mellitus; BP, blood pressure; MAP, mean arterial pressure; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CAD, coronary artery disease; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; CCS, Canadian Cardiovascular Society; NYHA, New York Heart Association; LDL, low density lipoprotein, HDL, high density cholesterol; ASA, acetylsalicylic-acid; ACEi/ARB, angiotensin converting enzyme inhibitors/angiotensin receptor blockers; NS, not significant; NA, not applicable