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Table 2 Baseline characteristics of T2DM patients with and without overweight

From: Impact of overweight on left ventricular function in type 2 diabetes mellitus

 

T2DM patients with overweight

(n = 70)

T2DM patients without overweight

(n = 75)

p value

Clinical data

 Age, years

59 ± 14

61 ± 13

0.31

 Female, n (%)

36 (51)

31 (41)

0.22

 Body mass index, kg/m2

30 ± 4

22 ± 2

< 0.05

 Heart rate, bpm

72 ± 13

70 ± 11

0.25

 DM duration, years

12 ± 8

10 ± 10

0.31

 Hypertension, n (%)

46 (66)

39 (53)

0.11

 Dyslipidemia, n (%)

55 (79)

35 (47)

< 0.05

Blood exam and urinary test

 HbA1c, %

8.5 ± 1.6

8.7 ± 2.5

0.53

 Low-density lipoprotein, mg/dL

107 ± 31

110 ± 37

0.52

 Triglyceride, mg/dl

165 ± 75

138 ± 89

< 0.05

 eGFR, mL/min/1.73 m2

72 ± 24

77 ± 26

0.24

Medical treatment

 CCB, n (%)

33 (47)

15 (20)

< 0.05

 ACEI/ARB, n (%)

41 (59)

30 (41)

< 0.05

 β-Blocker, n (%)

7 (10)

6 (8)

0.78

 Statin, n (%)

44 (63)

25 (34)

< 0.05

 Insulin, n (%)

41 (59)

32 (43)

0.07

 DPP-4I, n (%)

38 (54)

39 (53)

0.85

 GLP-1RA, n (%)

12 (17)

2 (2)

< 0.05

 Sulfonylurea, n (%)

18 (26)

18 (24)

0.84

 α-GI, n (%)

12 (17)

17 (23)

0.36

 Thiazolidine, n (%)

10 (14)

4 (5)

0.09

 Metformin, n (%)

44 (63)

35 (47)

0.06

Echocardiography

 LV end systolic volume, mL

28 ± 10

25 ± 10

0.08

 LV end diastolic volume, mL

78 ± 21

72 ± 21

0.13

 LV ejection fraction, %

65 ± 5

66 ± 4

0.06

 Stroke volume, mL

64 ± 14

62 ± 11

0.34

 Left atrial volume index, mL/m2

31 ± 9

29 ± 8

0.08

 LV mass index, g/m2

84 ± 19

75 ± 21

< 0.05

 E/e′

11.1 ± 4.0

10.3 ± 4.1

0.26

 e′

5.8 ± 1.4

6.3 ± 1.8

0.06

 Global longitudinal strain, %

17.0 ± 2.4

18.9 ± 2.6

< 0.05

  1. Values are mean ± SD for normally distributed data and median and interquartile range for non-normally distributed data, or n (%)
  2. GFR estimated glomerular filtration rate, CCB calcium channel blocker, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, DPP-4I dipeptidyl peptidase-4 inhibitor, GLP-1RA glucagon like peptide-1receptor agonist, α-GI α-glucosidase inhibitor. Other abbreviations as in Table 1