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Table 1 Baseline characteristics of normal controls and T2DM patients

From: Impact of overweight on left ventricular function in type 2 diabetes mellitus

 

Controls

(n = 90)

T2DM patients

(n = 145)

p value

Clinical data

 Age, years

57 ± 15

60 ± 13

0.08

 Female, n (%)

50 (56)

67 (46)

0.16

 Body mass index, kg/m2

22.0 ± 3.9

25.4 ± 5.0

< 0.05

 Body mass index ≥ 25 kg/m2, n (%)

14 (16)

70 (48)

< 0.05

 Body mass index ≥ 30 kg/m2, n (%)

3 (3)

27 (19)

< 0.05

 Systolic blood pressure, mmHg

122 ± 14

129 ± 20

< 0.05

 Diastolic blood pressure, mmHg

72 ± 11

74 ± 12

0.27

 Heart rate, bpm

67 ± 11

75 ± 12

< 0.05

Echocardiography

 LV end systolic volume, mL

26 ± 9

26 ± 10

0.82

 LV end diastolic volume, mL

74 ± 22

75 ± 21

0.68

 LV ejection fraction, %

66 ± 5

66 ± 5

0.93

 Stroke volume, mL

67 ± 14

63 ± 13

< 0.05

 Left atrial volume index, mL/m2

26 ± 9

30 ± 9

< 0.05

 LV mass index, g/m2

71 ± 19

79 ± 21

< 0.05

 E/e′

8.4 ± 2.5

10.7 ± 4.0

< 0.05

 e′

9.0 ± 3.1

6.0 ± 1.6

< 0.01

 Global longitudinal strain, %

20.3 ± 2.0

18.0 ± 2.6

< 0.05

  1. Values are mean ± SD for normally distributed data and median and interquartile range for non-normally distributed data, or n (%)
  2. DM diabetes mellitus, LV left ventricular, E peak early diastolic mitral flow velocity, e′ spectral pulsed-wave Doppler-derived early diastolic velocity from the septal mitral annulus