Skip to main content


Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis

Fig. 5

Quantification of atherosclerotic lesions from aortas of ApoE−/− mice. Aortas were harvested from ApoE−/− mice fed a LFD or HFHCD for 8 weeks while receiving daily subcutaneous injections of PBS or liraglutide from weeks 2 to 8. a Representative aorta for each treatment group with en face staining. Percent lesion areas were quantified using ImageJ for b total aorta, c aortic arch, d thoracic aorta, e abdominal aorta and f iliac bifurcation. Error bars are representative of 10 aortas per group (n = 10). Statistical analysis was performed carrying out Mann–Whitney t tests comparing all groups. Statistical significance was considered when *p < 0.05, **p < 0.01 and ***p < 0.001. p > 0.05 was considered NS. Stars above the columns represent comparisons made against the LFD control while capped lines indicate comparisons made between other groups

Back to article page