TY - JOUR AU - Pretorius, Etheresia AU - Page, Martin J. AU - Engelbrecht, Lize AU - Ellis, Graham C. AU - Kell, Douglas B. PY - 2017 DA - 2017/11/02 TI - Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains JO - Cardiovascular Diabetology SP - 141 VL - 16 IS - 1 AB - We have previously shown that many chronic, inflammatory diseases are accompanied, and possibly partly caused or exacerbated, by various coagulopathies, manifested as anomalous clots in the form of ‘dense matted deposits’. More recently, we have shown that these clots can be amyloid in nature, and that the plasma of healthy controls can be induced to form such clots by the addition of tiny amounts of bacterial lipopolysaccharide or lipoteichoic acid. Type 2 diabetes (T2D) is also accompanied by raised levels of LPS. SN - 1475-2840 UR - https://doi.org/10.1186/s12933-017-0624-5 DO - 10.1186/s12933-017-0624-5 ID - Pretorius2017 ER -