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Table 2 Comparison of glycemic parameters between patients with and without cardiovascular autonomic neuropathy over 2 years

From: Glycated albumin and its variability as an indicator of cardiovascular autonomic neuropathy development in type 2 diabetic patients

 

CAN (−)

CAN (+)

P value

Mean GA over 2 years (%)

17.0 ± 3.1

23.5 ± 6.8

<0.001

GA variability over 2 years

 Standard deviation of GA (%)

1.7 ± 1.1

4.6 ± 2.6

<0.001

 Adjusted SD of GA (%)

1.6 ± 1.0

4.4 ± 2.4

<0.001

 %CV of GA

9.7 ± 5.3

19.1 ± 8.3

<0.001

Measurement of GA, n

7.0 (6.0–8.0)

7.0 (7.0–8.0)

0.006

Mean HbA1c over 2 years (%)

7.0 ± 0.8

8.5 ± 1.4

<0.001

HbA1c variability over 2 years

 Standard deviation of HbA1c (%)

0.4 ± 0.3

0.9 ± 0.5

<0.001

 Adjusted SD of HbA1c (%)

0.4 ± 0.3

0.9 ± 0.5

<0.001

 %CV of HbA1c

6.0 ± 3.5

10.9 ± 4.9

<0.001

Measurement of HbA1c, n

8.0 (7.0–8.0)

8.0 (7.0–8.0)

0.056

  1. Data are presented as mean ± SD or median (25th to 75th percentile)
  2. Adjusted SD = SD/[n/(n − 1)]0.5, where n is the number of HbA1c or GA measurements
  3. CAN cardiovascular autonomic neuropathy, GA glycated albumin, HbA1c hemoglobin A1c, SD standard deviation, CV coefficient of variance
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Cardiovascular Diabetology

ISSN: 1475-2840