Impact of renal function on the underlying pathophysiology of coronary plaque composition in patients with type 2 diabetes mellitus

Table 4 Biochemical markers

Variables		Group 1 (n = 40)	Group 2 (n = 31)	p value
TNF-α, pg/ml	1.2 (0.9–1.75)	1.1 (0.9–1.5)	1.6 (0.9–1.9)	0.041
IL-6, pg/ml	1.8 (1.2–2.75)	1.8 (1.175–2.725)	2 (1.3–2.6)	0.812
hs-CRP, ng/ml	432 (243–781.5)	430 (260–812.5)	448 (227–717.5)	0.469
Adiponectin, μg/ml	7 (5.6–11.35)	6.7 (5.35–10.85)	8.2 (6.25–12.05)	0.219
MDA-LDL, U/l	83 (64.5–102.5)	77.5 (62.75–95.25)	85 (68–107.5)	0.321
Total homocysteine, nmol/ml	10.5 (8.85–13)	99.9 (8.55–12.375)	11.2 (9.9–14.65)	0.022
ADMA, μmol/l	0.46 ± 0.07	0.45 ± 0.07	0.47 ± 0.07	0.169
8-iso PGF2α, pg/ml	17 (13.5–23.5)	16 (13–19.25)	19 (15.5–27)	0.027

Values are mean ± SD. Group 1: ≥ 60 mL/min/1.73 m², Group 2: < 60 mL/min/1.73 m². p values for Group 1 vs. Group 2
TNF tumor necrosis factor; IL-6 interleukin-6; hs-CRP high sensitivity C-reactive protein; MDA-LDA malondialdehyde LDL; ADMA asymmetric dimethylarginine; PGF2α prostaglandin F2α; other abbreviations as in Table 1

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