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Table 3 IVUS

From: Impact of renal function on the underlying pathophysiology of coronary plaque composition in patients with type 2 diabetes mellitus

Variables

Overall (n = 71)

Group 1 (n = 40)

Group 2 (n = 31)

p value

QCA analysis

 Reference diameter, mm

2.7 ± 0.7

2.6 ± 0.6

2.8 ± 0.8

0.186

 Diameter stenosis, %

21.9 ± 12.9

23.6 ± 13.2

19.8 ± 12.2

0.078

Plaque location, n (%)

 LAD

51 (33.3)

27 (32.9)

24 (33.8)

0.360

 LC

54 (35.3)

28 (34.2)

26 (36.6)

0.177

 RCA

48 (31.4)

27 (32.9)

21 (29.6)

0.983

Diameter stenosis, %

 LAD

22.1 ± 12.5

23.6 ± 14.0

20.4 ± 10.6

0.361

 LC

23.3 ± 16.8

24.8 ± 14.0

20.2 ± 13.1

0.219

 RCA

21.1 ± 11.7

20.9 ± 11.1

21.3 ± 12.6

0.906

Gray-scale IVUS analysis

 EEM CSA, mm2

14.0 ± 4.9

14.0 ± 4.8

14.1 ± 5.0

0.953

 Lumen CSA, mm2

7.8 ± 3.7

7.5 ± 3.4

8.2 ± 3.9

0.284

 Plaque CSA, mm2

6.2 ± 2.5

6.5 ± 2.6

5.8 ± 2.4

0.109

 Remodeling index

0.81 ± 0.22

0.83 ± 0.25

0.78 ± 0.20

0.181

 EEM volume, mm3

140.3 ± 48.9

139.9 ± 48.1

140.7 ± 50.0

0.953

 Lumen volume, mm3

78.4 ± 36.5

74.9 ± 34.3

82.4 ± 38.8

0.282

 Plaque volume, mm3

61.9 ± 25.2

65.0 ± 25.7

58.3 ± 24.3

0.109

 Plaque volume,  %

45.0 ± 12.4

47.2 ± 11.6

42.41 ± 12.9

0.070

iMap IVUS analysis

 Fibrous volume, mm3 (%)

38.4 ± 14.1 (64.6 ± 12.8)

40.2 ± 13.2 (63.6 ± 13.4)

36.3 ± 14.8 (65.6 ± 11.9)

0.027 (0.106)

 Lipid volume, mm3 (%)

7.1 ± 4.4 (10.9 ± 3.5)

7.5 ± 4.6 (10.8 ± 3.4)

6.7 ± 4.2 (10.9 ± 3.7)

0.281 (0.421)

 Necrotic volume, mm3 (%)

15.4 ± 12.2 (22.3 ± 9.6)

16.7 ± 12.4 (23.1 ± 10.1)

13.8 ± 11.8 (21.4 ± 8.9)

0.102 (0.109)

 Calcified volume, mm3 (%)

1.5 ± 1.7 (2.3 ± 1.9)

1.9 ± 2.0 (2.5 ± 2.0)

1.1 ± 1.1 (2.0 ± 1.7)

0.063 (0.251)

  1. Values are mean ± SD (%). Group 1: ≥ 60 mL/min/1.73 m2, Group 2: < 60 mL/min/1.73 m2. p values for Group 1 vs. Group 2. EEM CSA, lumen CSA, and plaque CSA were measured at the minimum lumen CSA site in each plaque
  2. IVUS intravascular ultrasound; QCA quantitative coronary angiography; LAD left anterior descending artery; LC left circumflex artery; RCA right coronary artery; EEM external elastic membrane; CSA cross-sectional area