Table 4 Characteristics, risk factors, and diagnostic and therapeutic procedures for aortic aneurysm and dissection admissions in type 2 diabetes mellitus (T2DM) versus non-diabetic patients, according to year of study (2002, 2006, 2010, and 2014)
2002 | 2006 | 2010 | 2014 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
T2DM | No T2DM | p value | T2DM | No T2DM | p value | T2DM | No T2DM | p value | T2DM | No T2DM | p value | |
N (%)a,b | 390 (100) | 390 (100) | NA | 615 (100) | 615 (100) | NA | 753 (100) | 753 (100) | NA | 841 (100) | 841 (100) | NA |
Age adjusted rate per 100.000 inhabitants | 2.03 | NA | NA | 2.93 | NA | NA | 3.3 | NA | NA | 3.45 | NA | NA |
Male sex, n (%) | 364 (93.33) | 364 (93.33) | NA | 591 (96.1) | 591 (96.1) | NA | 710 (94.29) | 710 (94.29) | NA | 802 (95.36) | 802 (95.36) | NA |
Age, mean (SD)a,b | 69.84 (9.03) | 69.84 (9.03) | NA | 71.06 (8.12) | 71.06 (8.12) | NA | 71.43 (8.08) | 71.43 (8.08) | NA | 72.41 (7.85) | 72.41 (7.85) | NA |
40–59 years, n (%) | 56 (14.36) | 56 (14.36) | NA | 60 (9.76) | 60 (9.76) | NA | 55 (7.3) | 55 (7.3) | NA | 51 (6.06) | 51 (6.06) | NA |
60–69 years, n (%) | 106 (27.18) | 106 (27.18) | 177 (28.78) | 177 (28.78) | 234 (31.08) | 234 (31.08) | 247 (29.37) | 247 (29.37) | ||||
70–79 years, n (%) | 184 (47.18) | 184 (47.18) | 288 (46.83) | 288 (46.83) | 350 (46.48) | 350 (46.48) | 376 (44.71) | 376 (44.71) | ||||
≥ 80 years, n (%) | 44 (11.28) | 44 (11.28) | 90 (14.63) | 90 (14.63) | 114 (15.14) | 114 (15.14) | 167 (19.86) | 167 (19.86) | ||||
CCI, mean (SD)a,b | 2.48 (0.82) | 1.42 (0.82) | < 0.01 | 2.56 (0.84) | 1.49 (0.79) | < 0.01 | 2.59 (0.76) | 1.53 (0.79) | < 0.01 | 2.7 (0.84) | 1.59 (0.75) | < 0.01 |
Smoking, n (%)a,b | 139 (35.64) | 136 (34.87) | 0.802 | 238 (38.7) | 214 (34.8) | 0.145 | 323 (42.9) | 316 (41.97) | 0.702 | 363 (43.16) | 360 (42.81) | 0.879 |
Obesity, n (%)a,b | 19 (4.87) | 11 (2.82) | 0.149 | 32 (5.2) | 20 (3.25) | 0.099 | 79 (10.49) | 28 (3.72) | < 0.01 | 82 (9.75) | 45 (5.35) | 0.001 |
Hypertension, n (%)a,b | 213 (54.62) | 139 (35.64) | < 0.01 | 367 (59.67) | 269 (43.74) | < 0.01 | 470 (62.42) | 371 (49.27) | < 0.01 | 541 (64.33) | 430 (51.13) | < 0.01 |
Lipid metabolism disorders, n (%)a,b | 47 (12.05) | 20 (5.13) | 0.001 | 129 (20.98) | 83 (13.5) | 0.001 | 292 (38.78) | 200 (26.56) | < 0.01 | 427 (50.77) | 292 (34.72) | < 0.01 |
Renal diseases, n (%)a,b | 31 (7.95) | 28 (7.18) | 0.686 | 67 (10.89) | 62 (10.08) | 0.635 | 114 (15.14) | 84 (11.16) | 0.021 | 147 (17.48) | 118 (14.03) | 0.053 |
Atrial fibrillation, n (%)a,b | 38 (9.74) | 26 (6.67) | 0.112 | 58 (9.43) | 67 (10.89) | 0.376 | 90 (11.95) | 106 (14.08) | 0.212 | 157 (18.67) | 116 (13.79) | 0.007 |
CHF, n (%) | 22 (5.64) | 13 (3.33) | 0.100 | 29 (4.72) | 24 (3.9) | 0.493 | 44 (5.84) | 40 (5.31) | 0.638 | 41 (4.88) | 34 (4.04) | 0.407 |
Mechanical ventilation, n (%) | 36 (9.23) | 32 (8.21) | 0.593 | 55 (8.94) | 48 (7.8) | 0.483 | 36 (4.78) | 60 (7.97) | 0.009 | 61 (7.25) | 62 (7.37) | 0.919 |
HD/DP, n (%) | 7 (1.79) | 5 (1.28) | 0.566 | 18 (2.93) | 14 (2.28) | 0.467 | 16 (2.12) | 23 (3.05) | 0.240 | 25 (2.97) | 24 (2.85) | 0.884 |
Thoracic aorta aneurysm open surgery, n (%)a,b | 9 (2.31) | 9 (2.31) | 0.903 | 22 (3.58) | 30 (4.88) | 0.198 | 25 (3.32) | 46 (6.11) | 0.005 | 43 (5.11) | 50 (5.95) | 0.379 |
TEVAR, n (%) | 0 (0) | 0 (0) | NA | 0 (0) | 0 (0) | NA | 25 (3.32) | 16 (2.12) | 0.133 | 37 (4.4) | 32 (3.8) | 0.508 |
Abdominal aorta aneurysm open surgery, n (%)a,b | 86 (22.05) | 94 (24.1) | 0.454 | 111 (18.05) | 112 (18.21) | 0.940 | 100 (13.28) | 128 (17) | 0.038 | 137 (16.29) | 153 (18.19) | 0.281 |
EVAR, n (%)a,b | 19 (4.87) | 22 (5.64) | 0.640 | 93 (15.12) | 76 (12.36) | 0.139 | 232 (30.81) | 190 (25.23) | 0.013 | 312 (37.1) | 291 (34.6) | 0.250 |
LHS, mean (SD)a,b | 15.63 (16.07) | 12.88 (12.95) | 0.008 | 11.82 (12.11) | 11.44 (16.71) | 0.644 | 11.28 (18.3) | 10.92 (13.32) | 0.669 | 9.43 (13.33) | 9.63 (13.24) | 0.760 |
In-hospital mortality, n (%)a | 56 (14.36) | 50 (12.82) | 0.447 | 77 (12.52) | 78 (12.68) | 0.920 | 82 (10.89) | 90 (11.95) | 0.446 | 68 (8.09) | 84 (9.99) | 0.118 |