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Table 2 Laboratory profile

From: Relation between low-density lipoprotein cholesterol/apolipoprotein B ratio and triglyceride-rich lipoproteins in patients with coronary artery disease and type 2 diabetes mellitus: a cross-sectional study

Variables

All cases n = 684

CAD (+)

CAD (−)

p value among the 4 groups

DM (+) n = 60

DM (−) n = 90

p value between the 2 groups

DM (+) n = 118

DM (−) n = 416

p value between the 2 groups

Lipids

 TC (mg/dL)

195 ± 38

176 ± 364,7

179 ± 314,7

0.380

196 ± 36

201 ± 38

0.064

< 0.0001

 LDL-C (mg/dL)

109 ± 31

97 ± 274,5

97 ± 254,5

0.710

109 ± 29

114 ± 31

0.209

< 0.0001

 HDL-C (mg/dL)

58 ± 17

51 ± 114,9

56 ± 15

0.012

56 ± 18

59 ± 17

0.029

0.0004

 non-HDL-C (mg/dL)

138 ± 35

126 ± 343,6

123 ± 284,7

0.866

140 ± 36

142 ± 35

0.363

< 0.0001

TRLs-related markers

 TG (mg/dL)*

122 (88/186)

192 (106/210)1

125 (86/173)5

0.128

145 (109/221)3

115 (83/176)

< 0.0001

0.003

 VLDL fraction (%)

12.9 ± 6.6

14.7 ± 6.92

13.5 ± 6.91,5

0.341

15.3 ± 6.94

11.9 ± 6.2

< 0.0001

< 0.0001

 RLP-C (mg/dL)*

5.4 (4.0/8.0)

5.3 (3.5/8.7)

4.9 (3.5/7.1)

0.271

6.0 (4.4/9.4)

5.3 (4.0/7.7)

0.027

0.096

 apo B (mg/dL)

90 ± 22

85 ± 211

83 ± 173,6

0.640

92 ± 21

92 ± 22

0.943

0.0012

 apo C-II (mg/dL)

4.6 ± 2.1

5.2 ± 2.62,8

4.3 ± 1.96

0.044

5.1 ± 2.42

4.4 ± 1.9

0.005

0.0009

 apo C-III (mg/dL)

10.2 ± 3.8

10.6 ± 4.6

9.9 ± 3.7

0.303

10.8 ± 4.4

10.0 ± 3.0

0.094

0.108

LDL oxidation marker

 MDA-LDL (U/L)

110 ± 46

106 ± 40

93 ± 333,6

0.051

114 ± 45

114 ± 49

0.207

0.001

Lipid ratio

 TG/HDL-C*

2.32 (1.44/3.60)

2.74 (1.93/4.46)1

2.29 (1.66/3.44)5

0.032

2.80 (1.84/4.58)2

2.04 (1.28/3.34)

0.018

0.007

Inflammatory marker

 WBC count (mm−3)

6096 ± 1630

6354 ± 1374

6126 ± 1271

0.258

6391 ± 1745

5960 ± 1685

0.013

0.037

 hs-CRP (mg/L)*

0.50 (0.30/1.20)

0.55 (0.22/1.78)

0.40 (0.20/0.90)

0.290

0.80 (0.40/1.60)

0.50 (0.20/1.10)

< 0.0001

0.322

  1. ANOVA and post hoc tests with Bonferroni correction were performed to test between-group differences
  2. TC total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, TG triglyceride, VLDL very LDL, RLP remnant-like particle, apo apolipoprotein, MDA malondealdehyde-modified, WBC white blood count, hs-CRP high-sensitivity C-reactive protein
  3. * Median interquartile range in parentheses
  4. 1p < 0.05, 2 p < 0.01, p < 0.001, p < 0.0001 vs. CAD (−) DM (−) group
  5. 5p < 0.05, p < 0.01, p < 0.001 vs. CAD (−) DM (+) group
  6. 8p < 0.05 vs. CAD (+) DM (−) group