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Table 4 Physiological and biochemical parameters of mice treated with vehicle or liraglutide

From: The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis

 

Vehicle

Liraglutide (17 nmol/kg/day)

Full

Early

Delayed

Number

6

6

9

8

Initial BW (g)

21.2 ± 0.4

21.9 ± 0.1

22.3 ± 0.3

21.9 ± 0.1

Final BW (g)

22.6 ± 0.5

23.3 ± 0.4

23.3 ± 0.3

23.6 ± 0.3

Heart rate (beats/min)

696 ± 28

722 ± 21

722 ± 8

715 ± 22

SBP (mmHg)

124 ± 2

119 ± 6

110 ± 4

115 ± 2

DBP (mmHg)

68 ± 13

66 ± 14

43 ± 6

62 ± 5

HbA1c (%)

4.6 ± 0.2

4.7 ± 0.2

4.7 ± 0.0

4.7 ± 0.1

FPG (mg/dL)

118 ± 7

114 ± 13

138 ± 8

136 ± 10

TC (mg/dL)

92 ± 8

89 ± 4

91 ± 1

91 ± 3

TG (mg/dL)

51 ± 3

52 ± 3

52 ± 3

60 ± 3

  1. Food and water intake were measured throughout the experimental period. The other parameters were evaluated at the end of the experiment, except for initial BW. The initiation time and the duration of liraglutide treatment were as follows: full, Days 1–29; Early, Days 1–14; Delayed, Days 15–29; the experiment design is illustrated in Fig. 3a
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Cardiovascular Diabetology

ISSN: 1475-2840