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Table 2 Circulating levels of different MPs subtypes in the study cohort

From: Circulating levels and characterization of microparticles in patients with different degrees of glucose tolerance

Origin

NGT (n = 53)

PreDM (n = 39)

T2DM (n = 68)

p value

AnnexinV+

3445 ± 500

4385 ± 800

14,991 ± 1700#

<0.001

Endothelial cells

 CD62E+

168 ± 48 ± 1

948 ± 118##

693 ± 81##

<0.0001

 AnnexinV+ CD62E+

65 ± 6

66 ± 10

100 ± 9#

<0.0001

Tissue factor

 CD142+

3.57 ± 0.39

2.67 ± 0.28

3.41 ± 0.32

0.127

 AnnexinV+ CD142+

37.14 ± 2.76

32.94 ± 2.82

29.88 ± 1.77

0.146

Leukocytes

 CD45+

277 ± 20

296 ± 17

308 ± 15

0.476

 AnnexinV+ CD45+

48.47 ± 5.06

35.23 ± 4.65

38.28 ± 3.07

0.121

Platelets

 CD62P+

220 ± 48

207 ± 74

135 ± 21

0.458

 AnnexinV+ CD62P+

124 ± 56

88 ± 28

113 ± 14

0.505

  1. Data presented as Mean ± ES (p value ANOVA and Bonferroni test)
  2. NGT glucose normotolerant, PreDM pre-diabetic, T2DM type 2 diabetic mellitus
  3. #p < 0.0001 vs NGT and PreDM
  4. ##p < 0.0001 vs NGT