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Table 1 Baseline clinical characteristics of the patients. Data presented for the total population and for the groups with or without cardiovascular events during the follow-up

From: Evolution and bad prognostic value of advanced glycation end products after acute heart failure: relation with body composition

 

Total population (n = 150)

Cardiovascular event (−) (n = 111)

Cardiovascular event (+) (n = 39)

p value

Age (years)

69.9 ± 11.0

68.7 ± 11.4

73.4 ± 9.1

0.024

Male, %

60.7

57.7

69.2

0.139

HTA, %

77.3

75.7

82.1

0.280

HLP, %

57.3

51.4

74.4

0.010

DM, %

46.0

43.2

53.8

0.169

Smoker, %

12.7

14.4

7.7

0.323

Previous AMI, %

18.0

11.7

35.9

0.001

Aetiology of HF, %

 Ischemic heart disease

28.0

24.6

46.2

0.001

 Valvular heart disease

15.3

13.5

20.5

 

 Hypertrophic cardiomyopathy

4.0

2.7

7.7

 

 Other causes

52.7

62.2

25.6

 

Systolic pressure, mmHg

114.9 ± 17.2

113.8 ± 17.0

118.1 ± 17.6

0.184

Diastolic pressure, mmHg

66.4 ± 12.1

67.0 ± 11.3

64.7 ± 14.1

0.322

Laboratory data

 Glucose, mg/dL

131.5 [103.0–177.7]

126.5 [102.5–176.2]

140.0 [104.5–192.7]

0.561

 NT-proBNP, pg/mL

2894 [1109–6822]

2386 [1048–4751]

6173 [1774–12723]

<0.001

 Hb, g/dL

13.2 ± 1.9

13.3 ± 1.8

12.9 ± 2.2

0.249

 HbA1c, %

6.1 [5.7–6.8]

6.1 [5.7–6.7]

6.1 [5.7–7.2]

0.430

 Triglyceride, mg/dL

94 [69–121]

93 [70–124]

99 [64–120]

0.641

 HDLc, mg/dL

39 [32–49]

39 [34–49]

39 [28–50]

0.432

 LDLc, mg/dL

83 [63–106]

91 [68–112]

63 [50–79]

<0.001

 eGFR MDRD, mL/min/1.73 m2

74.3 ± 30.0

80.1 ± 30.9

57.4 ± 19.2

<0.001

Echo- and electro-cardiogram data

 LVEF, %

42.9 ± 15.6

42.9 ± 14.6

42.7 ± 18.4

0.957

 LV end-diastolic volume, mL

156.6 ± 71.0

150.4 ± 69.2

180.1 ± 74.5

0.096

Body composition and nutrition

 BMI, kg/m2

29.3 [26.1–33.3]

28.9 [25.9–34.2]

29.6 [27.1–32.5]

0.560

 BF, %

37.7 ± 9.6

37.9 ± 10.0

36.9 ± 8.5

0.577

 LMI, kg/m2

17.5 ± 3.0

17.3 ± 2.9

18.1 ± 3.1

0.204

 Visceral fat, g

1878 ± 1114

1836 ± 1102

2001 ± 1158

0.459

 CONUT score

2 [1–4]

2 [1–4]

3 [2–5]

0.056

Medication, %

 ACE inhibitors and/or ARBs, %

89.3

91.9

82.1

0.083

 β blockers, %

78.7

79.3

76.9

0.459

 Ca channel blockers, %

13.3

13.5

12.8

0.578

 Statins, %

64.7

58.6

82.1

0.029

  1. ACE angiotensin-converting enzyme, AMI acute myocardial infarction, ARB angiotensin receptor blocker, BF body fat, BMI body mass index, CONUT controlling nutritional status score, DM diabetes mellitus, eGFR MDRD estimated glomerular filtration rate by modification of diet in Renal Disease formula, Hb haemoglobin, HbA1c glycated haemoglobin, HDLc high density lipoprotein cholesterol, HF heart failure, HLP hyperlipidaemia, HTA arterial hypertension, LDLc low density lipoprotein cholesterol, LMI lean mass index, NT-proBNP N-terminal pro b-type natriuretic peptide