Table 3 Events, crude incidence rates and hazard ratios of events by statin types

Composite outcome^a

 No of events/person-years

217/7032

398/16,840

342/18,287

41/2894

97/4461

 Absolute rates^b (95% CI)

30.9 (27.0–35.3)

23.6 (21.4–26.1)

18.7 (16.8–20.8)

14.2 (10.4–19.2)

21.7 (17.8–26.5)

 HR^c (95% CI)

1 (reference)

0.75 (0.64–0.89)

0.59 (0.50–0.70)

0.45 (0.32–0.62)

0.68 (0.54–0.87)

 aHR^d (95% CI)

1 (reference)

0.82 (0.68–0.98)

0.67 (0.55–0.82)

0.56 (0.39–0.81)

0.78 (0.60–1.01)

All-cause mortality

 No of events/person-years

177/7098

203/17,229

162/18,710

17/2947

33/4616

 Absolute rates (95% CI)

24.9 (21.5–28.9)

11.8 (10.3–13.5)

8.7 (7.4–10.1)

5.8 (3.6–9.3)

7.1 (5.1–10.1)

 HR (95% CI)

1 (reference)

0.45 (0.37–0.55)

0.32 (0.26–0.40)

0.22 (0.13–0.36)

0.27 (0.19–0.39)

 aHR (95% CI)

1 (reference)

0.61 (0.48–0.78)

0.49 (0.38–0.64)

0.39 (0.22–0.67)

0.39 (0.26–0.60)

Acute myocardial infarction (AMI)

 No of events/person-years

5/7094

26/17,168

21/18,670

2/2948

11/4590

 Absolute rates (95% CI)

0.7 (0.3–1.7)

1.5 (1.0–2.2)

1.1 (0.7–1.7)

0.7 (0.2–2.7)

2.4 (1.3–4.3)

 HR (95% CI)

1 (reference)

2.17 (0.83–5.65)

1.62 (0.61–4.30)

0.98 (0.19–5.03)

3.45 (1.20–9.94)

 aHR (95% CI)

1 (reference)

1.42 (0.53–3.78)

0.88 (0.32–2.40)

0.63 (0.12–3.33)

1.61 (0.54–3.78)

Non-fatal stroke

 No of events/person-years

34/7051

168/16,919

158/18,337

22/2896

53/4489

 Absolute rates (95% CI)

4.8 (3.4–6.7)

9.9 (8.5–11.6)

8.6 (7.4–10.1)

7.6 (5.0–11.5)

11.8 (9.0–15.5)

 HR (95% CI)

1 (reference)

2.07 (1.43–2.99)

1.80 (1.24–2.61)

1.59 (0.93–2.72)

2.47 (1.61–3.80)

 aHR (95% CI)

1 (reference)

1.82 (1.22–2.72)

1.67 (1.11–2.51)

1.64 (0.91–2.94)

2.42 (1.52–3.84)