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Table 2 Demographic and clinical data of diabetic PAD patients with Fontaine’s II and CLI

From: Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects

 

Fontaine’s II

CLI

P value

OR (95% CI)§

P value

(281)

(288)

Men/female (n)

166:115

176:112

0.275†

0.91 (0.4–2.1)

0.823

Age (years ± SD)

71.9 ± 3.4

72.7 ± 4.4

0.431*

1.00 (0.9–1.00)

0.476

Smoking (current) (%)

56 (19.9)

154 (53.4)

0.001†

3.43 (2.15–3.65)

0.001

Hypertension (%)

173 (61.6)

182 (63.2)

0.143†

0.89 (0.62–1.04)

0.327

CAD (%)

102 (36.3)

195 (67.7)

0.001†

3.74 (2.49–4.02)

0.001

Diabetes duration (years ± SD)

9.3 ± 3.1

15.7 ± 5.1

0.001†

4.37 (3.07–5.12)

0.001

Total cholesterol (mmol/L)

3.65 (1.12)

5.68 (1.83)

0.001†

2.05 (1.54–3.02)

0.001

HDL-C (mmol/L)

1.15 (1.01)

1.31 (1.09)

0.247†

0.85 (0.69–1.01)

0.296

LDL-C (mmol/L)

1.95 (0.87)

3.25 (1.43)

0.001†

2.69 (1.32–4.12)

0.001

Triglyceride (mmol/L)

1.95 (1.45)

1.93 (1.06)

0.473†

1.32 (0.71–1.58)

0.456

Fast glucose (mmol/L)

6.78 (1.84)

6.97 (2.46)

0.945†

1.02 (0.56–1.34)

1.001

Glycated hemoglobin (%)

7.25 (1.16)

7.33 (1.32)

0.854†

1.00 (0.43–1.15)

0.765

  1. Data are number (%) and standard deviation (SD)
  2. CAD coronary artery disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  3. * Statistical test performed with Student’s t test
  4. †Chi square test for categorical values
  5. §Logistic regression analysis. OR odds ratios, 95% CI 95% confidence intervals