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Table 2 Demographic and clinical data of diabetic PAD patients with Fontaine’s II and CLI

From: Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects

  Fontaine’s II CLI P value OR (95% CI)§ P value
(281) (288)
Men/female (n) 166:115 176:112 0.275 0.91 (0.4–2.1) 0.823
Age (years ± SD) 71.9 ± 3.4 72.7 ± 4.4 0.431* 1.00 (0.9–1.00) 0.476
Smoking (current) (%) 56 (19.9) 154 (53.4) 0.001 3.43 (2.15–3.65) 0.001
Hypertension (%) 173 (61.6) 182 (63.2) 0.143 0.89 (0.62–1.04) 0.327
CAD (%) 102 (36.3) 195 (67.7) 0.001 3.74 (2.49–4.02) 0.001
Diabetes duration (years ± SD) 9.3 ± 3.1 15.7 ± 5.1 0.001 4.37 (3.07–5.12) 0.001
Total cholesterol (mmol/L) 3.65 (1.12) 5.68 (1.83) 0.001 2.05 (1.54–3.02) 0.001
HDL-C (mmol/L) 1.15 (1.01) 1.31 (1.09) 0.247 0.85 (0.69–1.01) 0.296
LDL-C (mmol/L) 1.95 (0.87) 3.25 (1.43) 0.001 2.69 (1.32–4.12) 0.001
Triglyceride (mmol/L) 1.95 (1.45) 1.93 (1.06) 0.473 1.32 (0.71–1.58) 0.456
Fast glucose (mmol/L) 6.78 (1.84) 6.97 (2.46) 0.945 1.02 (0.56–1.34) 1.001
Glycated hemoglobin (%) 7.25 (1.16) 7.33 (1.32) 0.854 1.00 (0.43–1.15) 0.765
  1. Data are number (%) and standard deviation (SD)
  2. CAD coronary artery disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  3. * Statistical test performed with Student’s t test
  4. Chi square test for categorical values
  5. §Logistic regression analysis. OR odds ratios, 95% CI 95% confidence intervals