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Table 1 Demographic and clinical data of diabetic subjects with and without PAD

From: Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects

  WPAD PAD P value
(n = 824) (n = 569)
Men/female (n) 490:334 344:225 0.243
Age (years ± SD) 71.3 ± 4.4 70.7 ± 4.3 0.647*
Smoking (current) (%) 181 (22.0) 210 (36.9) 0.023
Hypertension (%) 335 (40.7) 355 (62.4) 0.029
CAD (%) 275 (33.4) 297 (52.2) 0.026
Diabetes duration (years ± SD) 12.1 ± 4.1 12.7 ± 4.9 0.095*
Total cholesterol (mmol/L) 4.97 (1.21) 4.87 (1.15) 0.239*
HDL-C (mmol/L) 1.21 (1.04) 1.23 (1.02) 0.329*
LDL-C (mmol/L) 2.96 (1.02) 2.87 (0.93) 0.206*
Triglyceride (mmol/L) 2.05 (1.54) 1.87 (0.98) 0.913*
Fast glucose (mmol/L) 6.89 (1.92) 7.01 (2.65)a 0.856*
Glycated hemoglobin (%) 7.37 (1.21) 7.24 (1.14) 0.763*
Treatment
 Diet only (%) 95 (11.5) 63 (11.1) 0.658
 Oral agents (%) 452 (54.9) 308 (54.1) 0.341
 Insulin therapy (%) 277 (33.6) 198 (34.8) 0.290
PAD
 1-Fontaine’s II (%)   281 (49.4)  
 2-Fontaine’s III (%)   163 (28.6)  
 2-Fontaine’s IV (%)   125 (22.0)  
  1. Data are number (%) and standard deviation (SD)
  2. CAD coronary artery disease, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  3. * Statistical test performed with Student’s t test
  4. Chi square test for categorical values