Fig. 2

HMGB-1, OPG, HsCRP and IL-6 serum and severity of PAD (Fontaine’s II and Critical Limb Ischemia). HMGB-1 high-mobility group box 1, OPG osteoprotegerin, HsCRP high-sensitivity C-reactive protein, IL-6 interleukin-6. Statistical test performed with Student’s t test. Data are shown as serum levels ± standard deviation. *P < 0.001