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Table 4 Univariate and multiple linear regression models for serum NGAL (A) and MMP-9/NGAL (B, log-transformed) concentrations in diabetic patients

From: Neutrophil gelatinase associated lipocalin (NGAL) is elevated in type 2 diabetics with carotid artery stenosis and reduced under metformin treatment

 

Univariate models

Multiple model

β ± SEa

p

β ± SEa

p

(A)

 Insulin

−21.75 ± 14.41

0.136

−10.97 ± 13.30

0.413

 Metformin

−74.67 ± 10.98

<0.0001

−74.60 ± 11.84

<0.0001

 Other anti-DM medication

−7.56 ± 14.07

0.593

−7.31 ± 11.21

0.517

 HBA1c

5.81 ± 6.70

0.388

14.12 ± 5.94

0.021

 log_Neutrophils

33.68 ± 18.69

0.076

9.57 ± 14.88

0.523

(B)

 Insulin

−0.29 ± 0.27

0.271

1.88 ± 1.02

0.072

 Metformin

−0.69 ± 0.247

0.0067

−0.57 ± 0.28

0.043

 Other anti-DM medication

0.0087 ± 0.258

0.973

0.04 ± 0.26

0.875

 HBA1c

0.05 ± 0.123

0.665

0.12 ± 0.14

0.405

 log_Neutrophils

0.821 ± 0.339

0.018

0.63 ± 0.35

0.073

  1. aRegression parameter (β) ± standard error (SE)