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Table 1 Patient characteristics

From: Impact of CD14++CD16+ monocytes on plaque vulnerability in diabetic and non-diabetic patients with asymptomatic coronary artery disease: a cross-sectional study

 

Total

N = 51

DM

N = 22

Non-DM

N = 29

p value

DM vs. non-DM

Age, years

70.2 ± 9.1

70.2 ± 9.2

70.2 ± 9.1

0.98

Male

38 (75)

17 (77)

21 (72)

0.69

BMI, kg/m2

23.7 ± 3.1

24.2 ± 2.6

23.3 ± 3.4

0.34

Systolic BP, mmHg

123.0 ± 12.5

122.6 ± 13.6

123.3 ± 11.7

0.86

Diastolic BP, mmHg

67.1 ± 9.4

65.3 ± 10.5

68.5 ± 8.4

0.24

eGFR, mL/min/1.73 m2

65.6 ± 17.8

64.0 ± 22.8

66.9 ± 13.1

0.57

CRP, mg/dL

0.10 ± 0.14

0.12 ± 0.16

0.08 ± 0.13

0.34

Total cholesterol, mg/dL

153.3 ± 24.9

150.1 ± 27.1

155.7 ± 23.4

0.43

LDL cholesterol, mg/dL

87.2 ± 20.1

84.7 ± 19.4

89.0 ± 20.8

0.45

HDL cholesterol, mg/dL

45.8 ± 12.5

44.9 ± 14.6

46.4 ± 10.9

0.68

Triglyceride, mg/dL

157.8 ± 84.7

161.2 ± 81.4

155.2 ± 88.6

0.80

Duration of DM, yrs

3.9 ± 1.1

10.0 ± 2.1

–

–

1,5-AG, μg/mL

16.0 ± 8.3

10.65 ± 6.51

20.23 ± 7.01

<0.01

FBS, mg/dL

104.9 ± 33.4

125.7 ± 41.2

89.1 ± 11.1

<0.01

Glycoalbumin, %

16.3 ± 3.3

18.7 ± 3.5

14.3 ± 1.1

<0.01

HbA1c, %

6.30 ± 0.76

6.95 ± 0.67

5.80 ± 0.31

<0.01

HOMA-R

2.01 ± 2.01

2.38 ± 2.29

1.74 ± 1.78

0.28

HOMA-β

100.4 ± 112.4

55.2 ± 38.1

133.1 ± 135.7

<0.01

LVEF, %

58.8 ± 8.5

61.0 ± 7.1

57.2 ± 9.3

0.12

Smoking, %

   

0.79

 Current

7 (14)

3 (14)

4 (14)

 

 Past

23 (45)

11 (50)

12 (41)

 

Past history

 Hypertension

40 (78)

20 (91)

20 (69)

0.06

 Dyslipidemia

48 (94)

22 (100)

26 (90)

0.18

Medications on admission

 Aspirin

45 (88)

19 (86)

26 (90)

0.52

 Thienopyridine

40 (78)

16 (73)

24 (83)

0.30

 Statin

42 (82)

19 (86)

23 (79)

0.39

 Beta-blocker

19 (37)

8 (36)

11 (38)

0.91

 ACE-I/ARB

32 (63)

17 (77)

15 (52)

0.06

 DPP4-I

16 (31)

16 (73)

0 (0)

<0.01

 Metformin

7 (14)

7 (32)

0 (0)

<0.01

 Sulfonylurea

1 (2)

1 (5)

0 (0)

0.43

 α-GI

4 (8)

4 (18)

0 (0)

<0.01

 Pioglitazone

1 (2)

1 (5)

0 (0)

0.43

 Glinide

1 (2)

1 (5)

0 (0)

0.43

  1. Data are represented as mean ± standard deviation, or as counts (%)
  2. 1,5-AG 1,5 anhydroglucitol, α-GI α-glucosidase inhibitor, ACE-I angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, BMI body mass index, BP blood pressure, CRP C-reactive protein, DM diabetes mellitus, DPP4-I dipeptidyl peptidase-4 inhibitor, FBS fasting blood sugar, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin, HDL high-density lipoprotein, HOMA-β homeostasis model assessment of β-cell function, HOMA-R homeostasis model assessment of insulin resistance, LDL low-density lipoprotein, LVEF left ventricular ejection fraction