Fig. 1

Cumulative incidence of outcomes during follow-up according to status of microvascular and macrovascular disease at baseline. a All-cause mortality. b Major macrovascular events. c Major clinical microvascular disease (p < 0.0001 for all). Black line absence of both macrovascular and microvascular disease. Blue line presence of microvascular disease alone. Green line presence of macrovascular disease alone. Red line presence of both microvascular and macrovascular disease