Table 3 Glucose and heart rate variability during 24-h and each time-phase in the miglitol group
Parameters | Miglitol-treated (n = 13 in CGM, 17 in Holter ECG) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
0700–0700 h (24-h) | 0700–1800 h (day-time) | 1800–0000 h (night-time) | 0000–0700 h (bed-time) | |||||||||
Day 1 | Day 2 | P value | Day 1 | Day 2 | P value | Day 1 | Day 2 | P value | Day 1 | Day 2 | P value | |
Mean glucose (mmol/L) | 8.66 (2.40) | 8.69 (2.62) | 0.867 | 8.55 (3.64) | 9.25 (3.29) | 0.872 | 9.24 (3.11) | 8.84 (2.40) | 0.330 | 7.29 (1.54) | 7.67 (2.10) | 0.220 |
Min glucose (mmol/L) | 5.31 (1.93) | 6.02 (1.37) | 0.025 | 6.53 (2.22) | 6.44 (1.25) | 0.832 | 6.68 (2.32) | 6.61 (1.47) | 0.868 | 5.70 (2.02) | 6.71 (1.90) | 0.024 |
Max glucose (mmol/L) | 12.39 (3.52) | 11.87 (3.80) | 0.157 | 11.84 (3.60) | 11.30 (3.86) | 0.121 | 11.78 (3.78) | 10.73 (3.74) | 0.019 | 8.74 (2.00) | 9.08 (2.89) | 0.405 |
∆ glucose (mmol/L) | 7.08 (3.07) | 5.85 (3.58) | 0.004 | 4.92 (2.41) | 4.51 (3.48) | 0.450 | 4.73 (2.50) | 3.82 (2.89) | 0.019 | 3.04 (1.69) | 2.37 (1.96) | 0.192 |
SD glucose (mmol/L) | 1.68 (0.90) | 1.42 (1.00) | 0.025 | 1.37 (0.63) | 1.26 (0.95) | 0.435 | 1.53 (0.70) | 1.15 (0.80) | 0.005 | 0.76 (0.45) | 0.54 (0.45) | 0.068 |
CV glucose (%) | 18.9 (6.4) | 15.6 (7.3) | 0.007 | 16.8 (11.2) | 12.8 (6.2) | 0.154 | 17.0 (12.9) | 12.5 (13.1) | 0.055 | 13.7 (8.1) | 9.8 (8.1) | 0.068 |
Mean HR (beats/min) | 71 (6) | 71 (8) | 0.643 | 69 (20) | 74 (8) | 0.893 | 71 (7) | 71 (8) | 0.968 | 66 (7) | 66 (7) | 0.423 |
Min HR (beats/min) | 59 (7) | 59 (7) | 0.888 | 63 (6) | 63 (8) | 0.521 | 62 (7) | 63 (8) | 0.336 | 60 (7) | 59 (7) | 0.482 |
Max HR (beats/min) | 96 (12) | 95 (13) | 0.916 | 93 (8) | 95 (13) | 0.461 | 90 (14) | 87 (10) | 0.246 | 86 (9) | 83 (12) | 0.139 |
SDNN (ms) | 96 (37) | 108 (43) | 0.028 | 89 (35) | 94 (32) | 0.277 | 87 (36) | 96 (38) | 0.077 | 77 (33) | 86 (36) | 0.120 |
RMSSD (ms) | 70 (30) | 80 (35) | 0.012 | 79 (42) | 81 (32) | 0.285 | 67 (27) | 75 (37) | 0.098 | 65 (24) | 73 (36) | 0.111 |
Mean LF/HF | 1.09 (0.42) | 1.14 (0.45) | 0.421 | 1.05 (0.66) | 1.10 (0.56) | 0.589 | 1.04 (0.55) | 1.11 (0.57) | 0.174 | 1.08 (0.49) | 1.05 (0.57) | 0.653 |
Min LF/HF | 0.06 (0.09) | 0.08 (0.13) | 0.154 | 0.12 (0.19) | 0.12 (0.20) | 0.972 | 0.12 (0.12) | 0.14 (0.16) | 0.174 | 0.13 (0.16) | 0.15 (0.17) | 0.575 |
Max LF/HF | 6.39 (3.09) | 5.78 (2.58) | 0.469 | 3.88 (3.03) | 4.46 (2.36) | 0.446 | 3.77 (2.50) | 4.05 (2.30) | 0.641 | 4.99 (2.50) | 4.51 (2.86) | 0.535 |