|
Parameters
|
Control (n = 17 in CGM, 18 in Holter ECG)
|
|---|
|
0700–0700 h (24-h)
|
0700–1800 h (day-time)
|
1800–0000 h (night-time)
|
0000–0700 h (bed-time)
|
|---|
|
Day 1
|
Day 2
|
P value
|
Day 1
|
Day 2
|
P value
|
Day 1
|
Day 2
|
P value
|
Day 1
|
Day 2
|
P value
|
|---|
|
Mean glucose (mmol/L)
|
7.66 (1.79)
|
7.72 (1.85)
|
0.758
|
7.91 (2.06)
|
7.77 (1.93)
|
0.640
|
8.25 (2.24)
|
8.50 (2.19)
|
0.296
|
6.77 (1.51)
|
6.96 (1.67)
|
0.508
|
|
Min glucose (mmol/L)
|
5.04 (1.47)
|
5.44 (1.35)
|
0.245
|
5.38 (1.57)
|
5.81 (1.10)
|
0.242
|
6.22 (1.53)
|
6.35 (1.44)
|
0.567
|
5.96 (1.48)
|
5.95 (1.72)
|
0.963
|
|
Max glucose (mmol/L)
|
11.24 (3.18)
|
11.26 (3.26)
|
0.969
|
10.62 (3.08)
|
10.28 (3.17)
|
0.333
|
10.52 (3.18)
|
10.85 (3.12)
|
0.411
|
7.68 (1.90)
|
8.17 (2.13)
|
0.189
|
|
∆ glucose (mmol/L)
|
6.21 (3.12)
|
5.82 (2.87)
|
0.411
|
5.24 (2.84)
|
4.47 (2.61)
|
0.056
|
4.30 (2.79)
|
4.50 (2.83)
|
0.453
|
1.72 (1.04)
|
2.22 (1.43)
|
0.045
|
|
SD glucose (mmol/L)
|
1.45 (0.87)
|
1.28 (0.69)
|
0.149
|
1.37 (0.85)
|
1.12 (0.67)
|
0.061
|
1.29 (0.86)
|
1.29 (0.87)
|
0.939
|
0.46 (0.30)
|
0.56 (0.38)
|
0.200
|
|
CV glucose (%)
|
18.3 (8.4)
|
16.4 (7.5)
|
0.175
|
16.3 (9.2)
|
13.8 (5.8)
|
0.190
|
14.0 (9.3)
|
15.0 (10.6)
|
0.493
|
8.3 (5.4)
|
10.0 (6.9)
|
0.200
|
|
Mean HR (beats/min)
|
68 (9)
|
70 (10)
|
0.002
|
69 (9)
|
70 (10)
|
0.157
|
66 (9)
|
66 (10)
|
0.168
|
66 (9)
|
66 (10)
|
0.400
|
|
Min HR (beats/min)
|
58 (8)
|
58 (8)
|
0.166
|
61 (10)
|
61 (8)
|
0.837
|
59 (8)
|
59 (9)
|
0.949
|
59 (8)
|
59 (9)
|
0.864
|
|
Max HR (beats/min)
|
89 (14)
|
93 (16)
|
0.012
|
85 (12)
|
89 (15)
|
0.152
|
82 (12)
|
87 (16)
|
0.015
|
82 (12)
|
87 (16)
|
0.074
|
|
SDNN (ms)
|
99 (35)
|
115 (42)
|
0.004
|
93 (38)
|
98 (30)
|
0.384
|
87 (33)
|
104 (41)
|
0.022
|
76 (30)
|
93 (40)
|
0.031
|
|
RMSSD (ms)
|
71 (29)
|
79 (34)
|
0.015
|
80 (40)
|
81 (31)
|
0.272
|
68 (27)
|
76 (36)
|
0.130
|
66 (24)
|
80 (39)
|
0.034
|
|
Mean LF/HF
|
1.11 (0.76)
|
1.24 (0.67)
|
0.044
|
0.97 (0.75)
|
1.21 (0.61)
|
0.012
|
1.15 (0.74)
|
1.22 (0.70)
|
0.312
|
1.28 (0.90)
|
1.28 (0.88)
|
0.968
|
|
Min LF/HF
|
0.04 (0.07)
|
0.08 (0.08)
|
0.093
|
0.09 (0.16)
|
0.11 (0.10)
|
0.608
|
0.13 (0.10)
|
0.17 (0.16)
|
0.118
|
0.12 (0.12)
|
0.12 (0.10)
|
0.989
|
|
Max LF/HF
|
6.77 (4.54)
|
8.17 (5.91)
|
0.188
|
4.18 (2.85)
|
6.97 (5.34)
|
0.013
|
4.84 (3.10)
|
5.78 (4.77)
|
0.245
|
6.03 (4.59)
|
5.75 (3.84)
|
0.618
|
- Values are mean (SD)
-
CGM continuous glucose monitoring, ECG electrocardiogram, SD standard deviation, CV coefficient of variation, HR heart rate, SDNN standard deviation of normal RR intervals, RMSSD root mean square of the differences in successive pairs of RR intervals, LF low frequency, HF high frequency
