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Table 2 Clinical and biochemical characteristics and sortilin levels in subgroup without coronary artery disease according to their diabetes mellitus status

From: Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus

 

DM (−), n = 93

DM (+), n = 23

P value

Age (years)

52.5 ± 8.3

54.5 ± 12.0

0.444

Men (%)

31.2

47.8

0.148

Body weight (kg)

65.7 ± 11.4

66.0 ± 12.4

0.916

BMI (kg/m2)

23.8 ± 2.8

25.1 ± 2.9

0.058

SBP (mmHg)

120.2 ± 16.0

121.7 ± 18.2

0.696

DBP (mmHg)

73.8 ± 12.3

75.3 ± 11.8

0.614

Glucose (mg/dl)

90.8 ± 12.9

147.3 ± 40.3

<0.001

HbA1c (%)

5.7 ± 0.3

8.5 ± 1.8

<0.001

TC (mg/dl)

202.6 ± 34.5

200.1 ± 39.2

0.764

LDL-C (mg/dl)

111.2 ± 24.3

118.3 ± 31.8

0.243

HDL-C (mg/dl)

52.6 ± 12.0

49.6 ± 10.3

0.272

TG (mg/dl)

129.0 ± 67.9

143.3 ± 65.5

0.255

hs-CRP (mg/dl)

0.17 ± 0.52

0.56 ± 0.98

<0.001

Sortilin (ng/ml)

1.34 ± 1.0

1.57 ± 0.54

0.006

HTN (%)

61.1

41.2

0.008

Dyslipidemia (%)

71.0

73.9

0.999

  1. Data are expressed as mean ± SD, or %. CAD coronary artery disease, DM diabetes mellitus, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL-C LDL cholesterol, HDL-C HDL cholesterol, TG triglyceride, HTN hypertension
  2. P values for student’s t test or nonparametric t test or Chi square test