|
Parameters
|
Dapagliflozin group
|
Metformin group
|
P value
|
|---|
|
White blood cell count (/μL)
|
|
Baseline
|
6378.6 ± 1553.5 (36)
|
6405.0 ± 1507.6 (36)
|
0.94
|
|
Week 16
|
6532.5 ± 1646.0 (35)
|
6372.6 ± 1700.5 (34)
|
0.69
|
|
Change
|
103.8 ± 1166.7 (34)
|
−106.2 ± 1183.0 (34)
|
0.46
|
|
P value within group
|
0.61
|
0.60
|
0.95
|
|
Red blood cell count (×104/μL)
|
|
Baseline
|
468.9 ± 40.2 (36)
|
468.3 ± 41.8 (36)
|
<0.001
|
|
Week 16
|
493.6 ± 41.6 (35)
|
456.6 ± 42.9 (34)
|
<0.001
|
|
Change
|
26.3 ± 16.3 (34)
|
−12.0 ± 17.5 (34)
| |
|
P value within group
|
<0.001
|
<0.001
| |
|
Hemoglobin (g/dL)
|
|
Baseline
|
14.3 ± 1.3 (36)
|
14.4 ± 1.3 (36)
|
0.70
|
|
Week 16
|
14.9 ± 1.4 (35)
|
14.2 ± 1.7 (34)
|
0.05
|
|
Change
|
0.7 ± 0.5 (34)
|
−0.2 ± 0.9 (34)
|
<0.001
|
|
P value within group
|
<0.001
|
0.21
| |
|
Hematocrit (%)
|
|
Baseline
|
42.6 ± 3.6 (36)
|
42.7 ± 3.3 (36)
|
0.94
|
|
Week 16
|
44.7 ± 3.5 (35)
|
41.8 ± 3.6 (34)
|
0.001
|
|
Change
|
2.2 ± 1.4 (34)
|
−0.9 ± 1.8 (34)
|
<0.001
|
|
P value within group
|
<0.001
|
0.006
| |
|
Platelet count (×104/μL)
|
|
Baseline
|
24.0 ± 6.4 (36)
|
24.0 ± 5.0 (36)
|
0.99
|
|
Week 16
|
23.9 ± 6.3 (35)
|
24.5 ± 4.7 (34)
|
0.64
|
|
Change
|
−0.3 ± 1.5 (34)
|
0.5 ± 2.2 (34)
|
0.09
|
|
P value within group
|
0.20
|
0.25
| |
|
Uric acid (mg/dL)
|
|
Baseline
|
5.6 ± 1.1 (37)
|
5.8 ± 1.2 (37)
|
0.41
|
|
Week 16
|
4.9 ± 1.1 (36)
|
5.9 ± 1.1 (36)
|
<0.001
|
|
Change
|
−0.6 ± 0.7 (36)
|
0.1 ± 0.6 (36)
|
<0.001
|
|
P value within group
|
<0.001
|
0.43
| |
- Data are mean ± standard deviation (n). P values show results of comparisons between groups by t test. P values within groups are results of paired t test
