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Table 1 Baseline patient characteristics according to diabetes status

From: Red blood cell distribution width as a prognostic marker in patients with heart failure and diabetes mellitus

Variables Total (N = 218) Diabetes (N = 71) No diabetes (N = 147) p value
Age (years), mean (SD) 73.9 (11.5) 73 (11.2) 74.4 (11.7) 0.399
Male gender, N (%) 132 (60.6) 45 (63.4) 87 (59.2) 0.658
Systolic blood pressure (mmHg), median [IQR] 155 [30] 160 [30] 155 [28] 0.837
Diastolic blood pressure (mmHg), median [IQR] 95 [10] 95 [10] 95 [13] 0.983
Heart rate (bpm), mean (SD) 116.2 (13.2) 113.5 (12.9) 117.9 (13.2) 0.334
HFrEF, N (%)b 157 (72) 48 (67.6) 109 (74.1) 0.313
EF (%), median [IQR] 37 [25] 37 [25] 37 [25] 0.127
Hypertension, N (%) 144 (66.1) 49 (69) 95 (64.6) 0.521
Atrial fibrillation, N (%) 109 (50) 33 (46.5) 76 (51.7) 0.411
Coronary artery disease, N (%) 75 (34.4) 26 (36.6) 49 (33.3) 0.229
NYHA class (admission)
 II 4 (1.8) 2 (2.8) 2 (1.4) 0.646
 III 58 (26.6) 17 (23.9) 41 (27.9)
 IV 156 (71.6) 52 (73.2) 104 (70.7)
B-blockera, N (%) 181 (83) 60 (84.5) 121 (82.3) 0.686
ACE-inhibitora, N (%) 138 (63.3) 40 (56.3) 98 (66.7) 0.138
Loop diureticsa, N (%) 193 (88.5) 63 (88.7) 130 (88.4) 0.949
MRA’sa, N (%) 132 (60.6) 42 (59.2) 90 (61.2) 0.77
Metformina, N (%) 60 (27.5) 60 (84.5)
Sulfonylurea analoguesa, N (%) 11 (5) 11 (15.5)
Insulina, N (%) 22 (10.1) 22 (30.9)
Hematocrit (%), mean (SD) 40.4 (4.6) 40.1 (5) 40.6 (4.3) 0.874
RDW (%), mean (SD) 15.2 (1.6) 15.2 (1.5) 15.3 (1.7) 0.744
K+ (mmol/L), mean (SD) 4.6 (0.8) 4.6 (0.8) 4.6 (0.7) 0.718
Uric acid (mg/dL), mean (SD) 7.2 (2.2) 7.1 (2) 7.3 (2.3) 0.841
Ferritin (ng/mL), median [IQR] 55 [72] 72 [82.1] 52 [59.5] 0.043
B12 (pg/mL), median [IQR] 257 [239] 258 [208] 250 [256] 0.660
Glucose (mg/dL), median [IQR] 133 [70] 182 [127] 116.5 [38] <0.0001
HbA1C (%), median [IQR] 6.3 [1.4] 7.6 [0.6] 6.1 [0.5] <0.0001
Urea (mg/dl), median [IQR] 56 [35] 58 [40] 54 [33] 0.652
EPO (mIU/mL), median [IQR] 13.5 [13.4] 14.6 [13.9] 12.5 [13.1] 0.156
Creatinine (mg/dL), median [IQR] 1.2 [0.7] 1.2 [0.7] 1.1 [0.6] 0.231
SGOT (IU/L), median [IQR] 27 [21] 23 [19] 27.5 [20] 0.263
SGPT (IU/L), median [IQR] 34 [23] 35 [18] 32.5 [29] 0.965
Na+(mmol/L), median [IQR] 140 [7] 138 [7] 141 [6] 0.015
WBC (103/mm3), median [IQR] 8.8 [4.2] 10.1 [4.6] 8.3 [4.4] 0.012
Folic Acid (ng/mL), median [IQR] 7 [4.2] 7.6 [4.6] 6.5 [3.7] 0.027
Weight (kg), median [IQR] 78 [25] 82 [27] 76 [21] 0.04
  1. aMonotherapy or combination therapy
  2. bHFrEF: EF < 50%