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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

Fig. 4

Expression levels of functional proteins and fractalkine by immunoblot assay. Average values ± SEM of SERCA2 (a), PLB (b), SERCA2/PLB ratio (c), PLB-P/PLB ratio (d), and fractalkine (e, CX3CL1) expression levels in left ventricular myocardium of CTRL (n = 2), D3 (n = 3), D3-UA (n = 4), and D3-UB (n = 4), in technical triplicate. Data are expressed in densitometric units. Sets of bands related to protein expression in 4 animals representative of the average behaviour observed in each group are reported in f. In columns 1–4 CTRL, D3, DR-UA, and D3-UB animals. *p < 0.05 significant differences vs CTRL; # p < 0.05 significant differences vs D3 (non-parametric statistical test Kruskal–Wallis and U Mann–Whitney test)

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