Cardiovascular Diabetology

Table 2 Correlations of baseline LFC with baseline lipid parameters

From: The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes

	Type 1 diabetes	T2 insulin naïve	T2 basal switch
	N = 249	N = 178	N = 225
Lipoprotein concentration
HDL-P, μmol/L
Total HDL	0.217	0.054	0.242
Large HDL	−0.094	−0.193	−0.216
Medium HDL	0.096	0.232	0.123
Small HDL	0.177	0.139	0.262*
LDL-P, nmol/L
Total LDL	0.228	0.190	0.206
IDL	0.205	0.197	0.076
Large LDL	−0.107	−0.184	−0.096
Small LDL	0.216	0.243	0.253*
VLDL-P, nmol/L
Total VLDL	0.100	0.113	0.116
Large VLDL	0.294*	0.398*	0.474*
Medium VLDL	0.160	0.087	0.119
Small VLDL	−0.024	0.048	−0.002
Lipoprotein size
HDL size, nm	−0.158	−0.183	−0.207
LDL size, nm	−0.187	−0.220	−0.183
VLDL size, nm	0.214	0.415*	0.460*
Apolipoproteins
Apo A1, mg/dL	0.138	0.133	0.118
Apo A2, mg/dL	0.247*	0.200	0.125
Apo B100, mg/dL	0.216	0.194	0.181
Apo C3, mg/dL	0.263*	0.225	0.298*
Other parameters
Adiponectin, ng/mL	−0.154	−0.251	−0.196
CETP, pmol/mL/min	0.009	−0.048	−0.031
CETP, μg/mL	−0.160	0.050	−0.004
Serum CEC, %	0.290*	−0.043	0.008
Free fatty acid, mEq/L	0.061	0.234	0.222

Data are Spearman r correlation coefficients
CEC cholesterol efflux capacity, CETP cholesterol ester transfer protein, HDL-P high density lipoprotein particle, LDL-P low density lipoprotein particle, T2 type 2 diabetes, VLDL-P very low density lipoprotein particle
* p < 0.001 for correlation

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