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Table 1 Clinical characteristics, serum LBP levels, and aortic PWV in all subjects as well as in men and women with type 2 diabetes

From: Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study

  All subjects Men Women p
N 196 101 95
Age (years) 61 ± 14 60 ± 13 62 ± 15 0.346
Duration of diabetes (years) 10 (3–18) 10 (2–20) 10 (5–16) 0.589
BMI (kg/m2) 27.1 ± 6.1 26.9 ± 5.5 27.3 ± 6.7 0.640
Waist circumference (cm) 92 ± 15 93 ± 13 91 ± 16 0.252
Systolic blood pressure (mmHg) 135 ± 20 135 ± 19 135 ± 20 0.962
Diastolic blood pressure (mmHg) 80 ± 12 81 ± 11 77 ± 13 0.022
Smoker n (%) 41 (20.9) 34 (33.7) 7 (7.4) <0.001
Antihyperglycemic agents n (%) 168 (85.7) 86 (85.2) 82 (86.3) 0.816
Statins n (%) 80 (40.8) 38 (37.6) 42 (44.2) 0.348
RAS inhibitors n (%) 72 (36.7) 34 (33.7) 38 (40.0) 0.358
Calcium-channel blockers n (%) 74 (37.8) 35 (34.7) 39 (41.1) 0.356
Albumin (g/dL) 4.0 ± 0.5 4.1 ± 0.6 4.0 ± 0.4 0.205
Creatinine (mg/dL) 0.95 ± 0.58 1.07 ± 0.59 0.82 ± 0.55 0.002
eGFR (mL/min/1.73 m2) 67.3 ± 23.7 66.3 ± 21.8 68.3 ± 25.7 0.548
Fasting glucose (mg/dL) 129 ± 37 127 ± 39 132 ± 34 0.367
HbA1c (%) 8.3 ± 1.9 8.3 ± 2.0 8.3 ± 1.7 0.950
HOMA-Ra 2.3 (1.5–3.7) 2.2 (1.5–3.4) 2.6 (1.6–3.9) 0.287
Triglycerides (mg/dL) 120 (85–163) 131 (88–176) 106 (76–156) 0.020
HDL-cholesterol (mg/dL) 45 ± 12 42 ± 10 48 ± 14 <0.001
LDL-cholesterol (mg/dL) 116 ± 42 120 ± 49 111 ± 32 0.105
hs-CRP (mg/L) 0.70 (0.27–1.58) 0.65 (0.25–1.12) 0.79 (0.29–1.95) 0.221
LBP (μg/mL) 18.2 ± 6.3 17.7 ± 5.8 18.7 ± 6.7 0.267
Aortic PWV (cm/s) 1194 ± 346 1224 ± 350 1162 ± 340 0.209
  1. Values are expressed as n (%), mean ± SD, or median (interquartile range). p values were determined by using χ2-test, unpaired t-test, or Wilcoxon rank-sum test, as appropriate, for comparison between men and women
  2. LBP lipopolysaccharide-binding protein, PWV pulse wave velocity, BMI body mass index, RAS renin-angiotensin system, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin A1c, HOMA-R homeostasis model assessment of insulin resistance, HDL high-density lipoprotein, LDL low-density lipoprotein, hs-CRP high-sensitivity C-reactive protein
  3. a N = 144 for all subjects, n = 79 for men, and n = 65 for women not receiving insulin therapy