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Table 1 Clinical data, medication and demographics

From: Retinal vessel diameters and reactivity in diabetes mellitus and/or cardiovascular disease

 

DM (n = 36)

CVD (n = 43)

DM and CVD (n = 37)

DM type: 1/2

2/34

–

1/36

Ethnicity: CA/SA/B

28/4/4

37/4/2

32/5/0

Age (years)

64 (10)

64 (11)

65 (9)

Gender (m/f)

24/12

30/13

32/5

SBP (mmHg)

130 (13)

125 (19)

125 (16)

DBP (mmHg)

75 (9)

75 (13)

67 (10)*

HR (beats per minute)

76 (14)

67 (11)*

72 (16)

IOP (mmHg)

15 (3)+

13 (2)

14 (2)

BMI (kg/m2)

31 (6)

27 (4)*

31 (6)

HbA1c (mmol/mol)

58 (15)

42 (3)*

61 (20)

DM duration (years)

11 (4.5–16)

–

10 (4–17)

Medications

 Calcium channel blocker

20, 56%

13, 30%

14, 38%

 ACEI/ARB

23, 64%

31, 72%

30, 81%

 Metformin

26, 72%

–

21, 57%

 Sulphonylurea

7, 19%

–

7, 19%

 DPP-4 inhibitor

8, 22%

–

6, 16%

 Insulin

15, 42%

–

14, 38%

 GLP-1 agonist

4, 11%

–

4, 11%

 Piaglitazone

4, 11%

 

2, 5%

 Lipid-lowering

26, 72%

41, 95%

36, 97%

 Aspirin

11, 31%

35, 81%

30, 81%

 Clopidogrel

1, 3%

7, 16%

7, 19%

 Nitrate

–

11, 26%

11, 30%

 Oral anticoagulant

6, 17%

5, 12%

5, 14%

 Beta-blocker

10, 28%

19, 44%

22, 59%

 Diuretic

18, 50%

9, 21%

18, 49%

 Thyroxine

6, 17%

6, 14%

3, 8%

Cardiovascular disease

 Coronary artery disease

–

31, 72%

30, 81%

 Peripheral artery disease

–

5, 12%

4, 11%

 Cerebrovascular disease

–

8, 19%

3, 8%

  1. Data presented as mean with standard deviation, or as number of subjects and percentage
  2. CA caucasian, SA South Asian, B black, M male, f female, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, IOP intraocular pressure, BMI body mass index, HbA1C glycated haemoglobin, DM diabetes mellitus, ACEI angiotensin-converting-enzyme inhibitor, ARB angiotensin receptor blockers, DPP-4 dipeptidyl peptidase-4 (‘gliptins’), GLP-1 glucagon-like peptide-1 (exenatide, liraglutide)
  3. * Different compared to the two other groups (p < 0.01)
  4. + Different to the CVD group (p < 0.01)