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Table 2 Non-pharmacological and pharmacological strategies to reduce the WAT/BAT ratio in VAT and EAT depots

From: Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes

  1. By changes in lifestyle and specific miRNA/gene expression, activation or transplantation of BAT, and bariatric surgery, the WAT/BAT ratio can be decreased. Metformin, PPARγ activators, anti-obesity drugs, statins, and more safely, incretins (stabilized by GLP-1R agonists and DPP-4 inhibitors), could also help to reduce this ratio
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Cardiovascular Diabetology

ISSN: 1475-2840