Glycemia and the cardioprotective effects of insulin pre-conditioning in the isolated rat heart

Table 2 Myocardial TNF-α and p-Akt contents at the end of reperfusion

	G100	InsG100	G600	InsG600
Number (n)	10	10	10	10
Myocardial TNF-α contents (pg/g dry heart weight)	1568 ± 458	2073 ± 424	1925 ± 229	1787 ± 464
Myocardial p-Akt/total Akt (Unit/mg)	11.4 ± 11.9	77.9 ± 19.6*^,†,‡	15.9 ± 10.9	53.6 ± 20.7*^,‡

Data are the mean ± SD
There was no difference among the groups in the cardiac muscle TNF-α concentration 20 min after reperfusion. The myocardial p-Akt/total-Akt in the InsG100 group was significantly higher than the other two groups and that in the InsG600 group was significantly higher we than those in the InsG100 and InsG600 at 20 min after reperfusion
* P < 0.05 vs. G100
^† P < 0.05 vs. InsG600
^‡ P < 0.05 vs. G600

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