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Table 4 Area under the ROC curve (AUC) for PAPP-A, other selected factors and a multivariate model (all factors)

From: Pregnancy-associated plasma protein-A is a stronger predictor for adverse cardiovascular outcomes after acute coronary syndrome in type-2 diabetes mellitus

 

All (n = 320)

T2DM (−) (n = 184)

T2DM (+) (n = 136)

AUC (95% CI)

p value

AUC (95% CI)

p value

AUC (95% CI)

p value

PAPP-A

0.80 (0.74–0.87)

Ref.

0.78 (0.67–0.88)

Ref.

0.79 (0.70–0.87)

Ref.

Diabetes

0.61 (0.54–0.67)

<0.001

    

Age

0.65 (0.58–0.73)

0.003

0.60 (0.48–0.72)

0.051

0.69 (0.59–0.79)

0.15

LVEF (%)

0.60 (0.52–0.68)

<0.001

0.66 (0.54–0.77)

0.06

0.52 (0.40–0.64)

<0.001

eGFR

0.66 (0.58–0.74)

<0.001

0.64 (0.52–0.76)

0.051

0.66 (0.56–0.77)

0.03

hsCRP

0.68 (0.60–0.75)

0.003

0.69 (0.57–0.80)

0.2

0.64 (0.52–0.76)

0.01

Multivariate (all above)

0.83 (0.77–0.89)

0.12

0.80 (0.70–0.90)

0.2

0.83 (0.75–0.91)

0.051

  1. AUC areas under the receiver operating characteristics curve, Multivariate a multivariate logistic regression using all factors presented in this table, p value comparison to the PAPP-A model; Ref. reference
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Cardiovascular Diabetology

ISSN: 1475-2840