Fig. 6
From: Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats
Imaging of the gastrocnemius muscle microcirculation to measure glycocalyx barrier properties. a Microvascular volume as a function of vessel diameter was determined for all vessel diameters (5–25 µm) for control rats (n = 5) and hyaluronidase treated rats (n = 6) and are not significantly different (p = 0.579). b The perfused boundary region (PBR) of hyaluronidase treated rats was significantly lower (p = 0.04) after hyaluronidase injection than the PBR of control rats (1.49 ± 0.07 vs. 1.99 ± 0.13 µm, respectively). Data are expressed as mean ± SEM, *p < 0.05 vs. control group