|
Variable
|
Placebo
|
n-3 PUFAs
|
p value
|
|---|
|
Fibrinogen (g/L)
|
|
Before
|
2.70 (2.60; 2.95)
|
2.74 (2.60; 2.97)
|
0.70
|
|
After
|
2.73 (2.58; 2.85)
|
2.72 (2.57; 2.87)
|
0.91
|
|
t50% (min)
|
|
Before
|
13.14 (±2.77)
|
13.55 (±3.07)
|
0.55
|
|
After
|
12.58 (±2.70)
|
13.76 (±2.59)
|
0.07
|
|
Lag time (min)
|
|
Before
|
2.94 (2.52; 3.27)
|
2.61 (2.33; 3.21)
|
0.35
|
|
After
|
2.94 (2.60; 3.28)
|
2.84 (2.56; 3.17)
|
0.75
|
|
Peak (nM)
|
|
Before
|
264.54 (220.08; 314.92)
|
247.05 (211.89; 287.34)
|
0.27
|
|
After
|
249.59 (190.94; 336.52)
|
243.83 (207.82; 293.65)
|
0.98
|
|
tt peak (min)
|
|
Before
|
5.87 (±0.92)
|
5.94 (±1.03)
|
0.76
|
|
After
|
5.62 (5.00; 6.96)
|
5.98 (4.96; 6.89)
|
0.89
|
|
F1.2 (pg/mL)
|
|
Before
|
41.40 (28.80;48.10)
|
34.70 (26.95; 46.85)
|
0.56
|
|
After
|
43.70 (33.90; 49.30)*
|
37.70 (27.40; 41.55)**
|
0.04
|
|
PR ADP (%)
|
|
Before
|
57.96 (±14.02)
|
54.44 (±14.27)
|
0.36
|
|
After
|
60.56 (±15.12)
|
58.19 (±12.52)
|
0.54
|
- Data shown as number (percentage) for categorical variables and mean (±standard deviation) or median (IQR) for continuous variables
-
Ks permeation coefficient, t50% clot lysis time, Lag time lag time peak height, ETP endogenous thrombin potential (an area under the thrombin concentration versus the time curve), Peak maximal thrombin concentration, tt peak time do peak, F1.2 prothrombin fragments, PR ADP platelet aggregation 10 µmol/L adenosine diphosphate, PR AA platelet aggregation 5 mmol/L arachidonic acid
- * p = 0.05 within the placebo group; ** p = 0.53 within the n-3 PUFA group
