Skip to main content

Table 1 Baseline characteristics of the study population (n = 74)

From: Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or inflammation in patients with atherosclerosis and type 2 diabetes

Variables

Placebo

N = 38

n-3 PUFAs

N = 36

Age (years)

66.7 (±6.8)

64.4 (±6.7)

Female sex, n (%)

12 (31.6)

14 (38.9)

Hypertension, n (%)

36 (93.7)

36 (100)

Hyperlipidemia, n (%)

22 (57.9)

28 (77.8)

Metabolic syndrome, n (%)

38 (100)

36 (100)

Obesity, n (%)

25 (65.8)

23 (63.9)

Waist circumference (cm)

107 (98; 113)

106 (99; 112)

Body mass index (kg/m2)

31.1 (28.1; 32.7)

30.9 (27.9; 34.7)

Body fat (%)

30.4 (27.4; 35.8)

34.0 (31.0; 43.0)

Visceral fat (%)

15.74 (±4.9)

16.25 (±4.5)

Total body water (%)

47.9 (43.9; 49.8)

47.5 (44.2; 49.2)

Muscle mass (kg)

53.5 (±11.5)

56.85 (±9.2)

DM2 duration (years)

10 (6; 15)

10 (6.5; 15)

CAD, n (%)

38 (100)

36 (100)

PAD, n (%)

14 (38.9)

12 (31.3)

Previous MI, n (%)

16 (42.1)

12 (33.3)

Previous PCI, n (%)

25 (65.8)

22 (61.1)

Creatinine (μmol/L)

84 (66; 94)

86.5 (74; 100)

eGFR (MDRD) (mL/min/1.73 m2)

78.6 (70; 90)

78 (69; 89)

Treatment, n (%)

 Beta blocker

31 (81.6)

30 (83.3)

 ACEI or ARB

33 (86.8)

34 (94.4)

 Long acting nitrate

5 (13.2)

6 (16.7)

 Calcium antagonist

13 (34.2)

19 (52.8)

 Statin

33 (86.8)

35 (97.2)

 Fibrate

0

1 (2.78)

 ASA

38 (100)

36 (100)

 Clopidogrel

19 (50)

14 (38.9)

 Metformin

24 (63.2)

25 (69.4)

 Sulfonylurea

14 (36.8)

17 (47.2)

 Acarbose

1 (2.6)

2 (5.6)

 DPP-IV

1 (2.6)

0

 Insulin

16 (42.1)

16 (44.4)

 PPI

10 (26.3)

12 (33.3)

 Loop diuretic

6 (15.8)

3 (8.3)

 Diuretic

11 (28.9)

11 (30.6)

 AA

6 (15.8)

3 (8.3)

  1. Data shown as number (percentage) for categorical variables and mean (±standard deviation) or median (IQR) for continuous variables
  2. CAD coronary artery disease, PAD peripheral artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, eGFR (MDRD) estimated glomerular filtration rate calculated by the abbreviated MDRD equation, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, ASA acetylsalicylic acid, PPI proton pump inhibitors, AA aldosterone antagonist