From: Human serum RNase-L level is inversely associated with metabolic syndrome and age
Variables | non-MetS | N | MetS | N | P value | Total | N |
---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Mean ± SD | |||||
Demographics | |||||||
 Age (year) | 52.9 ± 9.9 | 291 | 54.3 ± 8.2 | 105 | 0.206 | 53.3 ± 9.5 | 396 |
 Gender (% male) | 55.0% | 291 | 75.2% | 105 | <0.001 | 60.4% | 396 |
 Body weight (kg) | 62.3 ± 10.6 | 290 | 76.1 ± 13.3 | 104 | <0.001 | 66.0 ± 12.9 | 394 |
 BMI (kg/m2) | 23.1 ± 2.8 | 290 | 27.2 ± 4.3 | 104 | <0.001 | 24.1 ± 3.8 | 394 |
 Waist (cm) | 83.3 ± 8.0 | 291 | 94.5 ± 8.5 | 105 | <0.001 | 86.2 ± 9.6 | 396 |
 Percentage of body fat (%) | 25.6 ± 5.2 | 290 | 29.4 ± 4.3 | 103 | <0.001 | 26.6 ± 5.3 | 393 |
 Mass of body fat (kg) | 16.1 ± 4.7 | 290 | 22.3 ± 5.4 | 103 | <0.001 | 17.7 ± 5.6 | 393 |
 Systolic blood pressure (mmHg) | 115.4 ± 12.9 | 291 | 129.3 ± 17.0 | 105 | <0.001 | 119.1 ± 15.4 | 396 |
 Diastolic blood pressure (mmHg) | 69.1 ± 9.4 | 291 | 79.3 ± 11.9 | 105 | <0.001 | 71.8 ± 11.0 | 396 |
 Pulse pressure (mmHg) | 46.4 ± 8.0 | 291 | 50.1 ± 8.8 | 105 | <0.001 | 47.7 ± 10.2 | 396 |
 Mean arterial pressure (mmHg) | 84.5 ± 10.0 | 291 | 95.9 ± 13.2 | 105 | <0.001 | 87.7 ± 12.0 | 396 |
Blood chemistry | |||||||
 Fasting glc (mg/dl) | 93.1 ± 13.2 | 291 | 110.8 ± 35.9 | 105 | <0.001 | 97.8 ± 23.0 | 396 |
 HbA1c (%) | 5.6 ± 0.4 | 291 | 6.2 ± 1.2 | 105 | <0.001 | 5.7 ± 0.8 | 396 |
 Triglyceride (mg/dl) | 100.2 ± 48.8 | 291 | 198.8 ± 132.2 | 105 | <0.001 | 126.3 ± 90.8 | 396 |
 Total cholesterol (mg/dl) | 195.8 ± 34.7 | 291 | 195.6 ± 37.9 | 105 | 0.975 | 195.8 ± 35.5 | 396 |
 HDL-C (mg/dl) | 54.4 ± 12.4 | 291 | 40.9 ± 9.0 | 105 | <0.001 | 50.8 ± 13.1 | 396 |
 LDL-C (mg/dl) | 121.9 ± 30.0 | 291 | 122.3 ± 31.2 | 105 | 0.867 | 122.0 ± 30.2 | 396 |
 TP (g/dl) | 7.2 ± 0.4 | 291 | 7.3 ± 0.4 | 105 | 0.357 | 7.3 ± 0.4 | 396 |
Medical history and drug usage | |||||||
 Hypertension (%) | 13.4% | 291 | 46.2% | 105 | <0.001 | 22.0% | 396 |
 Diabetes (%) | 4.1% | 291 | 21.2% | 105 | <0.001 | 8.6% | 396 |
 Hyperlipidemia (%) | 9.2% | 291 | 29.8% | 105 | <0.001 | 14.6% | 396 |
 Drug for elevated BP (%) | 12.0% | 291 | 45.2% | 105 | <0.001 | 20.7% | 396 |
 Drug for elevated glc (%) | 4.8% | 291 | 18.3% | 105 | 0.001 | 8.3% | 396 |
 Drug for elevated TG (%) | 8.2% | 291 | 21.2% | 105 | 0.003 | 11.6% | 396 |
 RNase-L (μg/ml) | 18.4 ± 8.0 | 291 | 16.5 ± 6.4 | 105 | 0.013 | 17.9 ± 7.6 | 396 |