Table 1 Baseline characteristics of participants and cross-sectional associations with lipoprotein(a) (n = 815)
Baseline variables | Mean (SD), median (25th–75th), or n (%) | Age- and sex-adjusted % mean difference in Lp(a) (95% CI) per SD higher level or compared to reference group |
|---|---|---|
Baseline Lp(a), mg/dLa | 8.9 (4.5–22.2) | – |
Apo(a) isoform size, KIV repeats | 25 (4.5) | −38.0 (−41.0, −34.0)** |
Age, mean (SD), years | 58 (11.0) | 1.3 (−4.6, 7.6) |
Male sex, % | 403 (49.5) | −2.1 (−13.2, 10) |
Current smoking, % | 199 (24.4) | 13.0 (−1.8, 30.0) |
Alcohol consumption, gram/week | 10 (0–50) | −1.4 (−8.0, 5.7) |
Physical activity, Baecke score | ||
 Low | 148 (18.2) | [Reference] |
 Medium | 312 (38.3) | −16.0 (−29.0, 0.65) |
 High | 355 (43.6) | 0.1 (−16.0, 19.0) |
SES | ||
 Low | 504 (61.8) | [Reference] |
 Medium | 173 (21.2) | −0.1 (−14.0, 17.0) |
 High | 138 (16.9) | −17.0 (−30.0, −1.0) |
Systolic blood pressure, mmHg | 144 (21.0) | 1.6 (−5.0, 8.6) |
BMI, kg/m2 | 25 (3.7) | 2.3 (−3.7, 8.7) |
WHR | 0.89 (0.07) | 4.9 (−2.5, 13.0) |
LDL-C, mg/dLb | 137 (38.0) | 26.0 (19.0, 33.0)** |
Triglycerides, mg/dL | 130 (78.4) | 1.9 (−7.6, 4.3) |
hsCRP, mg/L | 0.14 (0.084–0.28) | 0.3 (−5.7, 6.6) |
HOMA-IR | 2.5 (1.6–3.7) | −1.6 (−7.4, 4.7) |
HbA1c, % | 5.4 (0.4) | 12.0 (5.3, 20.0)* |
Fasting glucose, mg/dL | 97 (9.5) | 0.7 (−5.3, 7.1) |