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Table 3 Baseline echocardiographic parameters associated with incident type 2 diabetes

From: Subclinical left ventricular diastolic dysfunction and incident type 2 diabetes risk: the Korean Genome and Epidemiology Study

Variables Univariate Multivariatea
OR (95% CI) P value OR (95% CI) P value P valueb
LA volume index (mL/m2) 1.013 (0.993–1.034) 0.189 1.017 (0.995–1.040) 0.133 0.933
LV mass index (g/m2) 1.016 (1.008–1.024) <0.001 1.009 (1.000–1.018) 0.040 0.283
LV hypertrophy (yes vs. no) 1.526 (1.088–2.141) 0.014 1.198 (0.806–1.780) 0.371 1.000
TDI Sm velocity (cm/s) 0.856 (0.772–0.949) 0.003 0.914 (0.816–1.024) 0.119 0.836
TDI Em velocity (cm/s) 0.742 (0.685–0.804) <0.001 0.867 (0.786–0.957) 0.004 0.031
E/Em ratio 1.147 (1.094–1.201) <0.001 1.076 (1.017–1.137) 0.010 0.071
LV diastolic dysfunction (yes vs. no) 2.239 (1.726–2.905) <0.001 1.617 (1.191–2.196) 0.002 0.014
  1. BMI body mass index, CI confidence interval, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment-insulin resistance, hsCRP high sensitivity C-reactive protein, LA left atrium, LV left ventricle, NGM normal glucose metabolism, OR odds ratio, TDI tissue Doppler imaging, TG triglycerides
  2. aModel was adjusted for age, sex, BMI ≥23 kg/m2, baseline glucose metabolism (NGM vs. prediabetes), hypertension, statin therapy, family history of diabetes, smoking status, alcohol intake, HOMA-IR, total cholesterol, TG/HDL ratio, and hsCRP. Each echocardiographic variable was tested separately in a multivariate model
  3. bCorrected P values using Bonferroni method for multiple comparisons