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Table 1 Baseline demographic and laboratory characteristics of the study participants developing or not developing type 2 diabetes at the follow-up

From: Subclinical left ventricular diastolic dysfunction and incident type 2 diabetes risk: the Korean Genome and Epidemiology Study

Variable All participants (n = 1817) Not developing type 2 diabetes (n = 1544) Developing type 2 diabetes (n = 273) P value
Age (years) 53.5 ± 6.7 53.1 ± 6.4 55.7 ± 7.5 <0.001
Male (%) 47.9 48.1 47.3 0.844
BMI (kg/m2) 24.5 ± 2.7 24.3 ± 2.6 25.4 ± 2.8 <0.001
Systolic BP (mmHg) 110.3 ± 13.5 109.4 ± 13.3 115.1 ± 13.6 <0.001
Diastolic BP (mmHg) 74.6 ± 9.5 74.3 ± 9.6 76.1 ± 9.1 0.002
Heart rate (bpm) 65.0 ± 6.9 64.9 ± 6.9 65.4 ± 6.9 0.318
Hypertension (%) 22.1 19.7 35.9 <0.001
Antihypertensive therapy (%) 16.8 14.5 29.7 <0.001
Fasting glucose (mg/dL) 90.9 ± 8.4 89.9 ± 7.8 96.3 ± 9.7 <0.001
2-h glucose (mg/dL) 134.3 ± 30.6 129.8 ± 28.4 160.0 ± 29.7 <0.001
Fasting insulin (µIU/mL) 8.70 ± 4.03 8.52 ± 3.99 9.71 ± 4.12 <0.001
HbA1c (%) 5.43 ± 0.35 5.39 ± 0.33 5.65 ± 0.38 <0.001
HOMA-IR 1.97 ± 0.98 1.91 ± 0.95 2.33 ± 1.06 <0.001
Family history of diabetes (%) 17.5 16.6 22.7 0.016
Glucose metabolism (%) <0.001
 NGM 43.4 49.2 10.6  
 Prediabetes 56.6 50.8 89.4  
Current smoker (%) 13.5 14.3 9.2 0.021
Current alcohol drinker (%) 50.0 50.1 49.5 0.896
Total cholesterol (mg/dL) 202.5 ± 34.2 202.1 ± 34.5 204.8 ± 32.9 0.217
HDL-cholesterol (mg/dL) 45.5 ± 10.6 45.9 ± 10.6 43.5 ± 10.5 0.001
Triglycerides (mg/dL) 134.6 ± 83.0 129.6 ± 79.5 162.3 ± 96.1 <0.001
Statin therapy (%) 2.5 1.4 3.4 0.007
hsCRP (mg/L) 1.39 ± 4.17 1.28 ± 3.93 2.03 ± 5.31 0.006
Creatinine (mg/dL) 0.95 ± 0.15 0.95 ± 0.14 0.96 ± 0.16 0.282
  1. BMI body mass index, BP blood pressure, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment-insulin resistance, hsCRP high sensitivity C-reactive protein, NGM normal glucose metabolism