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Table 4 Correlations of the changes between markers for body composition and the markers for cardio-metabolic risks in patients with type 2 diabetes

From: Luseogliflozin reduces epicardial fat accumulation in patients with type 2 diabetes: a pilot study

  Delta EFV Delta LAI Delta VFA Delta SFA
r p values r p values r p values r p values
Changes in body composition markers
 Body weight (kg) 0.301 0.113 −0.616 0.003 0.686 0.001 0.250 0.159
 Body mass index (kg/m2) 0.387 0.046 −0.531 0.012 0.719 <0.001 0.292 0.120
 EFV NA   0.154 0.264 −0.237 0.164 −0.075 0.379
 LAI 0.154 0.264 NA   −0.391 0.049 −0.168 0.245
 VFA (cm2) −0.237 0.164 −0.391 0.049 NA   0.272 0.130
 SFA (cm2) −0.075 0.379 −0.168 0.245 0.023 0.463 NA  
 Body fat (%) 0.103 0.342 −0.468 0.025 0.296 0.117 −0.149 0.277
 Total fat mass (kg) 0.166 0.255 −0.723 <0.001 0.284 0.127 0.082 0.374
 Total non-fat mass (kg) −0.063 0.402 0.224 0.186 −0.255 0.154 −0.082 0.374
 Skeletal muscle index 0.187 0.229 −0.154 0.271 0.143 0.285 0.350 0.047
Changes in cardio-metabolic markers
 HbA1c (%) 0.256 0.152 −0.150 0.277 0.073 0.387 0.282 0.128
 HOMA-IR −0.271 0.155 0.315 0.118 0.306 0.117 0.094 0.364
 ALT (U/l) −0.044 0.490 −0.170 0.251 0.249 0.159 −0.203 0.210
 Log CRP (mg/l) 0.493 0.019 −0.453 0.029 −0.039 0.438 0.302 0.112
 Log ACR (mg/g) −0.069 0.393 0.042 0.434 0.333 0.048 −0.069 0.393
 Adiponectin (μg/ml) −0.228 0.189 0.154 0.264 −0.167 0.261 −0.571 0.008
 Leptin (ng/ml) 0.146 0.295 0.115 0.330 0.378 0.044 −0.138 0.305
 Log interleukin 6 (pg/ml) −0.411 0.064 −0.318 0.115 0.296 0.142 0.007 0.490
  1. ACR albumin-to-creatinine ratio, ALT alanine transaminase, CRP C-reactive protein, DBP diastolic blood pressure, EFV epicardial fat volume, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment as an index of insulin resistance, LAI liver attenuation index, SBP systolic blood pressure, SFA subcutaneous fat area, VFA visceral fat area